Protein Alignment CG8654 and sv2a

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 560
• Identity: 105/560 - (18%)
• Similarity: 174/560 - (31%)
• Gaps: 194/560 - (34%)

  Fly   102 CESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFR 166
            |.|:....:...||.||::.|:.::|..|||.|||...|....:..:..........|..:...|
Zfish   190 CLSEPNKGMLGLIVYLGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCR 254

  Fly   167 FLVAVATAGTMTTSFVLLMEIVGPKKRE----------MVAILYQ-------IP-----FNIGHA 209
            .|..|...|::...|....|.:..:||.          |:..:|.       ||     |.:|.
Zfish   255 LLSGVGIGGSIPIVFSYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGS- 318

  Fly   210 SLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNK---- 270
                 ||....||.|.......|:..:..:..:|||||:....||.|::..||:::...|.
Zfish   319 -----AYQFHSWRVFVLVCAFPSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAKG 378

  Fly   271 --------APTETIR--PEIEAAYGALAA---RQPVKK--------GTVVDLFRTPYMRIKTIFM 314
                    ...:|::  .|:....|...|   |..:|.        |..:.:|...|.||..:.|
Zfish   379 YPERVFSVTTIKTVKQMDELVDMGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMM 443

  Fly   315 ANNWLVVCMVYYG---------------------------------------------------- 327
            | .|..:...|||
Zfish   444 A-VWFSMSFSYYGLTVWFPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNK 507

  Fly   328 --------------------------------TAQYVSALGGN---------------------- 338
                                            ...::|.|..|
Zfish   508 FLNLKMKSMVFEDSLFEECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNK 572

  Fly   339 ---------------IFISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLS 388
                           |:..:.:.....:||..:.||:...:||.:.|..|:..|.:....|:..:
Zfish   573 EGCMLDFSDENNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVISCVSCFFLSFGN 637

  Fly   389 TQAEAVRVTCATIGLFGA-SITFPNVY-LYGGELFPTVVRSSGVG----LCSMVGRIGSIVAPLI 447
            :::..:.:.|    |||. ||...|.. :...||:|:..|::..|    ||.:...:|..:....
Zfish   638 SESAMIALLC----LFGGISIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSF 698

  Fly   448 VDLAAYGLWVAPLIFGIFSILAMLGTIF---LPETRGTPL 484
            |.:..    ..|::|...::.|  |:..   ||||||..|
Zfish   699 VGITK----AVPILFASGALAA--GSFLALKLPETRGQVL 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	105/560 (19%)
		MFS	87..477	CDD:119392	98/551 (18%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	105/560 (19%)
		MFS	162..725	CDD:119392	98/551 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940