Protein Alignment CG8654 and Slc22a21

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_062697.1
• Gene: Slc22a21 / 56517
• MGIID: 1929481
• Length: 564
• Species: Mus musculus
• Alignment Length: 541
• Identity: 160/541 - (29%)
• Similarity: 258/541 - (47%)
• Gaps: 67/541 - (12%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA------------------------- 61
            |.:.:.:|::..:|...||::.......|:..|..:||.|
Mouse     5 DEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRNHSIPM 69

  Fly    62 ------PTPLSCK----------TENVTDPCSD---------ECSE-TEFDTSVFQSTIITEWNL 100
                  ..|..|:          :|...:|..|         .|.: .|:|..:|.|||:|||:|
Mouse    70 ETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDL 134

  Fly   101 TCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRP-AFLTCCFMQLITG--LIVCVSPYYWFY 162
            .|:....|.|:.|...:|:|.||.:.|..:||:||:. .|||   |.:.||  .|...|..:..:
Mouse   135 VCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLT---MAMHTGFSFIQVFSVNFEMF 196

  Fly   163 CLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAIL-YQIPFNIGHASLALFAYFIREWRWFQF 226
            .|...||.:........:|||..|::....|.:.|.| ..|.|..|...|.||||||||||....
Mouse   197 TLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLL 261

  Fly   227 SITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAPTETIRPEIEAAYGALAA 289
            :||:..::.....|.:|||||||.:.|::.::..|:.|.||.|  .||:....|.........::
Mouse   262 AITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSS 326

  Fly   290 RQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGT 354
            ::| :...:.||.|||.:||.||.....||.:.:.|:|.:.....|.|||:::..:.|.|.:|..
Mouse   327 KKP-QSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAY 390

  Fly   355 CLCALMTKYLGRKKTLLLSNGCSALG---LILLACLSTQAEAVRVTCATIGLFGASITFPNVYLY 416
            .|..|:.:::.|:.::.   |...||   |:|:..:.:....:..|...:|.||.:..:..||:|
Mouse   391 VLAWLLLQHVSRRYSMA---GSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVY 452

  Fly   417 GGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRG 481
            ..||:|||||:.|||:.|...|:|||::|..|.|.||...:..::.|..:||..:.|:|.||:.|
Mouse   453 TAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITLFFPESSG 517

  Fly   482 TPLPETLEDGETFGRKKKDQA 502
            ..||||:::.:...:.|:.|:
Mouse   518 VSLPETIDEMQKVKKLKQRQS 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	135/404 (33%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	155/517 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..564		2/7 (29%)