DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8654 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	512	Identity:	169/512 - (33%)
Similarity:	243/512 - (47%)	Gaps:	59/512 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSC---------------KTENVT 73
            |:|.:|:|..:|......|.|....|.:|..|.:|.|...|..|               |..|:|
Zfish     7 ILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLT 71

  Fly    74 DPCS-----DEC---SETEFD------------TSVF----------QSTIITEWNLTCESKQLA 108
            .|..     :.|   :..|.|            ||..          .||:|||::|.||:|..:
Zfish    72 VPLDSKGQYESCKMFTPVEMDIEDIEHYGINTTTSCIDGWVYKAPKDSSTLITEFDLVCENKVYS 136

  Fly   109 SLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVAT 173
            ..||||.|.|:|.|::|||..||:||||.|.|...|:|.::|:.|..||..:.|...||:|....
Zfish   137 EASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALRFVVGTTI 201

  Fly   174 AGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIY 238
            :|....:|||..|..|..||.:..||....|.||...|:..||.||.||..|..::....:|.||
Zfish   202 SGISINTFVLGTEWCGSAKRALFTILSHCFFAIGLMLLSGVAYGIRNWRVLQLVLSAPVGLFFIY 266

  Fly   239 IWLVPESPRWLFTTGKLDKSIKILEKIAKCN-KAPTETIRPEIEAAYGALAARQPVKKGTVVDLF 302
            .|::|||.|||.|.||||.:.:.:.|.|:.| :..:|.:..::|       |....|..|::|||
Zfish   267 YWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLDKME-------AENTAKSSTMIDLF 324

  Fly   303 RTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRK 367
            |..|:|.:.:.|...|.|..:||||.:..|...|.:|:::..|......|....|..:.:..||:
Zfish   325 RVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCFPLIQRFGRR 389

  Fly   368 ---KTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSG 429
               ..:||..|.:.|   ::..:..:...|....|.||.|..:.:|..||:|..||:|||||.:|
Zfish   390 ICQSVVLLLGGTACL---IIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQNG 451

  Fly   430 VGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPE 486
            |||.||..|:..|:||||..|..|...:..:|:|....:....|..||||..|.|.:
Zfish   452 VGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQD 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	149/428 (35%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	142/403 (35%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.910