Protein Alignment CG8654 and SVOP

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_061181.1
• Gene: SVOP / 55530
• HGNCID: 25417
• Length: 548
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 115/436 - (26%)
• Similarity: 192/436 - (44%)
• Gaps: 56/436 - (12%)

  Fly    88 SVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLI 152
            |:....:..||.|  .|.|:|.|: |:|.:|::..|.|:|..:|:|||:..........|..|::
Human   105 SILAPQLHCEWRL--PSWQVALLT-SVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGIL 166

  Fly   153 VCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYF 217
            ...:|.|.:..:.|.||.....| :..|..|..|.:..|.|....:|.::.:.||.....:.|.|
Human   167 SAFAPVYSWILVLRGLVGFGIGG-VPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVF 230

  Fly   218 IRE---WRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPE 279
            :..   |||......:..::|.:..:.:|||.|:...:|..:|:|..|::||..|.||
Human   231 VMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAP------- 288

  Fly   280 IEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSAL--GGNIF-I 341
              ...|.|...:...:|.:.||| ||:.|..|:.:...|......|||.....:.|  .|::. |
Human   289 --MPLGKLIISRQEDRGKMRDLF-TPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGI 350

  Fly   342 SN---AIAAGVGI---------------------PGTCLCALMTKYLGRKKTLLLSNGC----SA 378
            |:   |:.|...:                     ||..:...:...||||||:.|   |    |.
Human   351 SSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMAL---CFVIFSF 412

  Fly   379 LGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIV 443
            ..|:|..|:......:.:..|...:.|.   |...|:|..|::||..|:.|:|.||.:.|:|:::
Human   413 CSLLLFICVGRNVLTLLLFIARAFISGG---FQAAYVYTPEVYPTATRALGLGTCSGMARVGALI 474

  Fly   444 APLIVD-LAAYGLWVAPLIFGIFSILAMLGTIFLP-ETRGTPLPET 487
            .|.|.. :....:::...::....:||.|.:.||| ||:|..|.|:
Human   475 TPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQES 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	114/434 (26%)
		MFS	87..477	CDD:119392	108/423 (26%)
SVOP	NP_061181.1	MFS_SVOP	87..509	CDD:340999	108/423 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940