DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and oatx

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	546	Identity:	162/546 - (29%)
Similarity:	255/546 - (46%)	Gaps:	84/546 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCKTENVTDPCSD---------- 78
            ::.::|.|.|:|:....::.:.........|.:.|.|......|:..|||...:|
Zfish     6 LLDEVGGFGRFQMIHVTLLSIPGLLMASQNLLNNFTAGVPEHHCRIPNVTTAMNDSTTTLLRAFI 70

  Fly    79 ---------ECS----------------------ETE-------FDTSVFQSTIITEWNLTCESK 105
                     :||                      :||       :|.|.|.|:|::||:|.|..:
Zfish    71 PLDSSLTLSKCSRYKDTQWHLITDKLSHGNATELQTEGCADGWTYDKSEFISSIVSEWDLVCTLR 135

  Fly   106 QLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVA 170
            .|..:||:|.|.|:|.|:|:||..:||:||:...:...|...:.|....::|.|..||:||||..
Zfish   136 PLKQMSQTIYMGGVLTGAIIFGGLSDRFGRKALLIWSYFQLALLGSFTALAPSYVVYCIFRFLTG 200

  Fly   171 VATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVF 235
            ::.:|.:..:..|.:|.:..|.|.:|..|....|..|...||..||.:|:||..|.::.:...:|
Zfish   201 MSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDWRKIQMAVCLPFFIF 265

  Fly   236 VIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKG--TV 298
            .:|.|...||.|||...|:.::::|:|.::||.|..|..|.:..:|.....:.......|.  ||
Zfish   266 FMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKPEMTEKITLEELESHMQKEVQSSKSIYTV 330

  Fly   299 VDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKY 363
            .||.|||.||..::.:...|......|||.|..:...|.||::...|...|..|...:..||..:
Zfish   331 FDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLMQVIFGAVDFPAKLVALLMLSF 395

  Fly   364 LGRKKTLLLSNGCSALGLILLACLSTQA----------EAVRVTCATIGLFG---ASITFPNVYL 415
            |||:    |:.|         |||...|          |.::||...:.:.|   .|.:|..|||
Zfish   396 LGRR----LTQG---------ACLLVSASIIFANIFVPEDMQVTRTALAVLGKGFTSASFTCVYL 447

  Fly   416 YGGELFPTVVRSSGVGLCSMVGRIGSIVAP--LIVD--LAAYGLWVAPLIFGIFSILAMLGTIFL 476
            :.|||:|||:|.:|:|..|.:.||||:.||  ||:|  |.|    :..:::|..:::|.|....|
Zfish   448 FTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPA----LPSIVYGGSAVIAGLIAFLL 508

  Fly   477 PETRGTPLPETLEDGETFGRKKKDQA 502
            |||...|||:|::|.|....||.:.|
Zfish   509 PETLNIPLPDTIDDVEEKWEKKNNTA 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	140/420 (33%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	132/408 (32%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.050