DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and slc22a15.1

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_031751719.1	Gene:	slc22a15.1 / 448510	XenbaseID:	XB-GENE-959503	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	500	Identity:	149/500 - (29%)
Similarity:	243/500 - (48%)	Gaps:	40/500 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IGDFRRYQLFF-FFIVLLCKFGTGWHTLGHIFLAAPTPLSCKTENVTD------------PCSDE 79
            :|:...||::. |.:.:|.:..:....:....|.|..|.....:::|.            |...|
Frog    36 VGEMGIYQIYLSFLLAVLLQLYSATEAIIITILGATPPYHWMNDSLTANGSRGKQYGSQLPAEGE 100

  Fly    80 CSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCF 144
            .....||.:.  ::|::||.|...:....|:|.|:...|:|.|.|.||..:||:||:|.::|...
Frog   101 HGHVVFDGNF--TSIVSEWFLVGGAAYEVSVSSSVYFGGVLIGVISFGQLSDRFGRKPVYVTGLA 163

  Fly   145 MQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHA 209
            ::::..::..::|.:..:.|.||||.|...|....:||||.|.:|.........|..:.|.:|.|
Frog   164 LEVVFAVMNALTPIFPLFLLTRFLVGVMNGGMSLVAFVLLNECIGASYWAAAGSLGSLCFAVGIA 228

  Fly   210 SLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAP 272
            ..||..||||.||.....:.:.....:.....:|||||||...|:|.::.:.|..:.:.|  |..
Frog   229 QFALIGYFIRSWRLLALLVNVQGAAVLALSLCIPESPRWLHAQGRLREAQESLLSLGRRNRRKVT 293

  Fly   273 TETIRP-EIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALG 336
            :.|:.| :.::|:.|          .::.::....:|.:|:.|...|.|..:||||.......||
Frog   294 SFTLCPRQKDSAHSA----------NILTIYSNAILRQRTLIMMWVWFVCSLVYYGLTLSSGDLG 348

  Fly   337 GNIFISNAIAAGVGIPGTCLCALMT--KYLGRKKTL--LLSNGCSALGLILLACLSTQAEAVRV- 396
            |:|:::.|::....:|...||..:.  |.:||:.:|  .|..|..|..||:|....|.:..:.|
Frog   349 GDIYLNLALSGLAELPAYPLCMYLINHKRVGRRGSLAGFLCVGGGACLLIMLVPGKTGSGPLSVL 413

  Fly   397 ---TCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVA 458
               |.:.:|....|..|..||:|..||:||.||:.|:|:|||..|||.|:||.|..| .:..|..
Frog   414 NSQTLSLLGKLNISAAFNIVYIYSSELYPTCVRNLGMGVCSMFSRIGGIIAPFIPAL-RFAHWAL 477

  Fly   459 P-LIFGIFSILAMLGTIFLPETRGTPLPETLED--GETFGRKKKD 500
            | ::||...:.|.|.::.||||...||||||.|  |..:.|.:.|
Frog   478 PFIVFGAAGVSAGLLSLLLPETLSAPLPETLADLRGAPYRRLEPD 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	131/413 (32%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	122/401 (30%)
slc22a15.1	XP_031751719.1	MFS	90..497	CDD:421695	126/419 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920