Protein Alignment CG8654 and F23F12.13

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001033356.1
• Gene: F23F12.13 / 3896740
• WormBaseID: WBGene00044455
• Length: 528
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 124/554 - (22%)
• Similarity: 219/554 - (39%)
• Gaps: 150/554 - (27%)

  Fly    32 RRYQLFFF---FIVLLCKFGTGWHTLGHIFLAAPTPLSCKTENVTDP----------------CS 77
            |.:.|.||   |.:..|     ...:..||......|||     .||                ||
 Worm     8 RFHWLCFFLWQFALFFC-----CQQIFSIFYNFSPGLSC-----DDPSFQFSKPKCKLSKSEICS 62

  Fly    78 D---ECSETEFDTSVFQSTIITEWNLTCESKQL-ASLSQSIVMLGILFGSILFGMFADRYGRRPA 138
            :   .||:...:.:.|.| ::.::.:.|.:|.. |:...:|..:|:|.|:|.:|...|.:||:|.
 Worm    63 ELTANCSKIVIEEAPFHS-MVQDFKMFCGTKAYDAAWVATIQFIGVLIGAITYGHLGDHFGRKPV 126

  Fly   139 FLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIP 203
            ......:.::.|:....:|.:..:..|||:|..:.|..:...:..::|.:.|::|    :..:..
 Worm   127 SFFGISVGILFGVASGFAPSWEVFAAFRFIVGTSIASILIVFYAYILEFIEPEQR----VFLRSF 187

  Fly   204 FNIGHASL--ALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKL----------- 255
            ||.|:|.|  .|..:....||....:.::.|:..:..:.::||||:| |.|.|.
 Worm   188 FNWGYARLVFTLACFICGYWRSAAIATSLLSLPILPVLLILPESPKW-FNTKKRFRDARAAEKRV 251

  Fly   256 ------------DKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMR 308
                        |:||:|.||:.:                       :..|..|:.|||.:..:.
 Worm   252 AWLSGIPYVNDEDQSIEISEKLEE-----------------------KSTKIYTMKDLFTSWTIA 293

  Fly   309 IKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVG-------------IPG------- 353
            .:||.:.:.|....:..:|:......|.||.::|..::..|.             :|.
 Worm   294 YRTIVVGSLWFSTSLSAFGSDLNSGNLAGNFYLSQFVSGAVTAFAKIFVFLLDTYVPSFDRRRLH 358

  Fly   354 --------TCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGAS--- 407
                    .|.|.:|.      ..:|..:.|.:.|...||.:            .|.:.|.|
 Worm   359 QYPQIAMILCYCVIMV------LMILPESDCGSQGSRDLAII------------IINIIGVSFIE 405

  Fly   408 ITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDL------AAYGLWVAPLIFGIFS 466
            ||:...||...|.|||.:|:.|:|.||::.|.|:::||.:..|      |.|.     ::..|.:
 Worm   406 ITWDACYLVAVECFPTKIRTIGIGTCSLLARTGALLAPQMAYLSDIYRPAPYA-----VVCSIGT 465

  Fly   467 ILAMLGTIFLPETRGTPLPETLEDGE--TFGRKK 498
            |..::..:|||:|:|..| ..|:..|  .:.|||
 Worm   466 ISLLISCVFLPDTKGVDL-AALDPTEELDYDRKK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	97/457 (21%)
F23F12.13	NP_001033356.1	MFS	74..476	CDD:475125	97/453 (21%)