Protein Alignment CG8654 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 159/545 - (29%)
• Similarity: 260/545 - (47%)
• Gaps: 71/545 - (13%)

  Fly    22 DPIISQIGDFRRYQ-LFFFFI----------VLLCKFGTG------W-HTLGH------------ 56
            :.::||:|...|:| |...||          :||..|...      | |.|.:
Human     4 EELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGSGNETGILS 68

  Fly    57 ----IFLAAP-----TPLSCK-------------------TENVTDPCSDECSETEFDTSVFQST 93
                :.::.|     .|..|:                   :|..|:||.|   ...:|.|.|.||
Human    69 EDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVD---GWVYDQSYFPST 130

  Fly    94 IITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSP 157
            |:|:|:|.|:.:.|.|:.|.:::.|:|.|.|:.|..:||:||| ..|..|.:|| ||......:|
Human   131 IVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRR-FILRWCLLQLAITDTCAAFAP 194

  Fly   158 YYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWR 222
            .:..||:.|||...::...::.:.:.:.|.:.|..:.:|.||.....:||...|...||..|:|:
Human   195 TFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGALSIGQIILGGLAYVFRDWQ 259

  Fly   223 WFQFSITI-FSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAPTETIRPEI--EA 282
            ......:: |.:.|::..||| ||.|||..|.|||:.:|.|.|:|:.|  |...||:..|:  ..
Human   260 TLHVVASVPFFVFFLLSRWLV-ESARWLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRST 323

  Fly   283 AYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAA 347
            ....|.|.|  .|.||.||||.|.||.:...:........:.:|||...:..:|.|||:...:..
Human   324 MQEELDAAQ--TKTTVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVNLQHVGSNIFLLQVLYG 386

  Fly   348 GVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPN 412
            .|.:...||..|...::||:.:.:|......|.::....:..:.:.:||..|.:|:..::.||.:
Human   387 AVALIVRCLALLTLNHMGRRISQILFMFLVGLSILANTFVPKEMQTLRVALACLGIGCSAATFSS 451

  Fly   413 VYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLP 477
            |.::..||.|||:|:...|:.....|||:.:|||::.|..:...:..:|:|||.|:..|....||
Human   452 VAVHFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLP 516

  Fly   478 ETRGTPLPETLEDGETFGRKKKDQA 502
            ||:..|||:|::|.|...:..|::|
Human   517 ETKNLPLPDTIKDVENQKKNLKEKA 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	132/407 (32%)
		MFS	87..477	CDD:119392	124/395 (31%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	152/521 (29%)
		MFS	143..516	CDD:119392	115/376 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464838at2759
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020