DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and CG3168

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	116/522 - (22%)
Similarity:	198/522 - (37%)	Gaps:	124/522 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RPQDPKAPKPLKPVTKTGDPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCK 68
            |.:....|:|..|:....:..|...|    |..|.:.::.:|...:....:..|.::...|
  Fly   120 RKKSVPLPEPTAPIVANFERAIELCG----YGKFHYILLAICGLVSTSEEMDVISMSFILP---- 176

  Fly    69 TENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRY 133
                    |.||                :.:|..|:|   ....||:.:|::.|:..:|..||.:
  Fly   177 --------SAEC----------------DLDLNTETK---GWLNSIIFIGMMVGAYFWGSIADSF 214

  Fly   134 GRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAI 198
            ||:...:...||.....:....|..|.|:.|||||...|..|:....:....|. .||.:....:
  Fly   215 GRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEF-QPKAKRGSML 278

  Fly   199 LYQIPF----NIGHASLA-------------LFAYFIREWRWFQFSITIFSIVFVIYIWLVPESP 246
            .:...|    |:..||||             .|.|  ..||.|....::.|.:....::.:||||
  Fly   279 SFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTY--NSWRIFLLVCSLPSFLVGFLLFYLPESP 341

  Fly   247 RWLFTTGKLDKSIKILEKIAKCN--KAPTETIRPEIEAAYGALAARQPVKK------GTVVD--- 300
            ::|.|.||.|:::.|...|...|  :.|.|.:..::|.....|.:...||.      ..:||
  Fly   342 KFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSR 406

  Fly   301 -LFRTPYMRIKTIFMANNWLVVCMVYYG----------------------------TAQYV---- 332
             ||::|.:|...:.:..|: ...:.|||                            ...||
  Fly   407 ALFKSPILRFTIVSITINF-TFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLA 470

  Fly   333 ----------SALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRKKTLL---LSNG-CSALGLIL 383
                      |.:..::|:.:.|:....:|...|..|....||||..|:   ::.| ||||...:
  Fly   471 KEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFV 535

  Fly   384 LACLSTQAEAVRVTCATIGLFGASITFPNVYL--YGGELFPTVVRSSGVGLCSMVGRIGSIVAPL 446
            .:  |.|...|.      .:|..:|:..|..|  ...|:|||.:|::||.:..:..|:|.|:..:
  Fly   536 RS--SVQNLVVS------AIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNI 592

  Fly   447 IV 448
            ::
  Fly   593 VI 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	102/441 (23%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	102/439 (23%)
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	109/489 (22%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	108/484 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040