Protein Alignment CG8654 and Slc22a14

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001101663.2
• Gene: Slc22a14 / 316061
• RGDID: 1306470
• Length: 630
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 134/539 - (24%)
• Similarity: 222/539 - (41%)
• Gaps: 80/539 - (14%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCKTE---------------NVT 73
            ::..||:|..:|.....:..:....:.:..|.|.||.......|.|.               |:|
  Rat    54 VLGAIGEFGTFQWRLVALTFIPSILSTFFLLSHHFLLTAQRPYCNTSWILQVGPNLTEDEQLNLT 118

  Fly    74 DP---------C--------------------SDECSETEFDTSVFQSTIITEWNLTCESKQLAS 109
            .|         |                    ::.|............::..|::|.|.::....
  Rat   119 VPRAPNGSFLTCLMYIPVPWDLDSIVHFGLNYTETCKHGWIYPFAHTRSLTNEFDLVCGNEPHEE 183

  Fly   110 LSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATA 174
            ..|::.:.|||.||:|||..:|:.||.|..|......||.|........::.|..|||.||.|:.
  Rat   184 NGQTVFLSGILTGSLLFGFLSDKLGRYPIILLSLLGILIFGFGTAFVNSFYQYLFFRFFVAQASV 248

  Fly   175 GTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWR--WFQFSITIFSIVFVI 237
            |....|..|:||.:..:.|....||....|.||...|..|||.|..||  :....:.:|.:  :.
  Rat   249 GYAICSVSLVMEWLVGEHRAQAIILQHCFFTIGVILLTGFAYKINHWRLLFLLGGVPMFPL--IC 311

  Fly   238 YIWLVPESPRWLFTTGKLDKSIKILEKIAKCNK--APTETIRPEIEAAYGALAARQPVK--KGTV 298
            .||::.||||||...||::::.|:|...|:.||  .|...:. |::.         |.|  |.::
  Rat   312 NIWVLQESPRWLMVKGKVEEAKKVLCYAAEVNKKTIPLNLLN-ELQL---------PGKKAKASI 366

  Fly   299 VDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKY 363
            :|.:...::....:.|...|..|..|....:..:...|.:|:....:.....:|....|.|:.:|
  Rat   367 LDFYTNQHLFKVVLAMGCVWFTVSYVSLTLSLKMKDFGLDIYFIQVVPCITAVPARLCCILLLEY 431

  Fly   364 LGRKKTLLLSNGCSALGLILLACLS-----TQAEAVRVTCATIGLFGASITFPNVYLYGGELFPT 423
            .|||.:|.|:     |.|:...|||     .:.::..:....:|.|..:.|....::|..||.||
  Rat   432 FGRKWSLNLT-----LSLVTFTCLSLLFVPEELKSTTILMLVLGEFSMAGTVSIFFIYTAELLPT 491

  Fly   424 VVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIF-GIFSILAMLGTIFLPETRGTPLPET 487
            ::||:|:|:.|:....|:|.:..|.......|   |:.| .:..|||:..:..:|||...||.::
  Rat   492 ILRSTGLGMVSIAWTAGAISSLAIFKQTKTQL---PIFFCCLCCILALCFSSLVPETGNQPLRDS 553

  Fly   488 LE----DGETFGRKKKDQA 502
            :|    |......|.||.:
  Rat   554 IEYCSRDSLEHKDKSKDSS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	109/406 (27%)
Slc22a14	NP_001101663.2	MFS	147..527	CDD:475125	106/399 (27%)