DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8654 and CG3690

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	587	Identity:	124/587 - (21%)
Similarity:	206/587 - (35%)	Gaps:	154/587 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PQDPKAPKPLKPVTKTGDPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCKT 69
            |.:...|||    .||.:   .||||..:.:....|...:...|.|...:..:..|.|..:....
  Fly     4 PSESGDPKP----HKTAE---HQIGDPPQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVY 61

  Fly    70 ENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYG 134
            |..|.......:|.:...|:....|:                .:|...|::..::|:|..||..|
  Fly    62 ETSTMSYILPSAECDLKLSLLDKGIL----------------NAITYAGMISSAVLWGYLADIKG 110

  Fly   135 RRPAFLTCCFMQLITGL---IVCV-----SPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPK 191
            ||..        ||.|.   .:||     |.......:|::|.....:|........|.|:.|.|
  Fly   111 RRNL--------LIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRK 167

  Fly   192 KREMVAILYQIPFNIGHASLALFAYFI--------------REWRWFQFSITIFSIVFVIYIWLV 242
            .|:.:.::..|.|:|...:|...|..|              ..|::|.....:.|::..:..:..
  Fly   168 HRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFF 232

  Fly   243 PESPRWLFTTGK----LDK----------------SIKIL--------EKIAKCNKAPTETIRP- 278
            ||||::|.:.|:    ||.                .||:|        :|.||....|||...|
  Fly   233 PESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPT 297

  Fly   279 ---EIEAAYGALAARQPVKKG--TVVDLFRTPYMRIK--------TIFMANN----WLVVCMVYY 326
               |::......:.:..::.|  .:..||..||:.:.        .:.:..|    ||.  .::.
  Fly   298 ECVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRLWLP--QLFA 360

  Fly   327 GTAQYVSALGG--------NI--------------------------------FISNAIAAGVGI 351
            ...:|.:.:.|        ||                                :.:|.|.||.|.
  Fly   361 SINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIITPSTYTNNLIVAGAGF 425

  Fly   352 PGTCLCALMTKYLGRK----KTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPN 412
            ....|...:...:|.|    ..||::.||| :|:..     :.:.|..|..|::.:...||:..:
  Fly   426 VAYMLAGFLVNLVGVKLIMTSGLLIAAGCS-IGMYW-----SSSAASTVALASLFVTMGSISATS 484

  Fly   413 VYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAP--LIFGIFSILAMLGTIF 475
            |......||||.:|:..|.|..|.||:||::..:... |..||...|  |:...|.:.......|
  Fly   485 VISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFP-ALMGLGCVPPFLMISAFMLAGCFMAAF 548

  Fly   476 LP 477
            ||
  Fly   549 LP 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	106/507 (21%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	104/503 (21%)
CG3690	NP_001284764.1	SP	42..549	CDD:273317	109/539 (20%)
		MFS	49..>195	CDD:119392	35/169 (21%)
		MFS	419..>550	CDD:119392	38/137 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010