Protein Alignment CG8654 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_803156.3
• Gene: Slc22a17 / 305886
• RGDID: 631405
• Length: 627
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 130/514 - (25%)
• Similarity: 209/514 - (40%)
• Gaps: 99/514 - (19%)

  Fly    43 LLCKFG------TGWH--------TLGHIFLAAPTPLSCKTENVTDP-CS-------DECSETEF 85
            |.|.:|      :||.        ::....|||..  :.:....||| ||       :.|.: ::
  Rat   120 LHCHYGALPPNASGWEQPPNSSGVSVAGAALAASA--ASRVVTSTDPSCSGFAPPDFNHCLK-DW 181

  Fly    86 DTS---VFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQL 147
            |.:   |..:..|.:|:|.|:......|.|.:.:||...|.:..|..|||:|||...|      |
  Rat   182 DYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVL------L 240

  Fly   148 ITGLIVCVSPYYWFYC--------------LFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAI 198
            ..||   |.|     |              ..|||:....||.....:::.:|:..|.:|..||:
  Rat   241 TLGL---VGP-----CGVGGAAAGSSTGIMTLRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVAL 297

  Fly   199 LYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIW--LVPESPRWLFTTGKLDKSIKI 261
            ..::....||......|...::||:.|..||...|:|:.|.|  |..||.|||....:::::..:
  Rat   298 AGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSV 362

  Fly   262 LEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYY 326
            |..:|:.|:...:.:..|.:.|...|....|:.  |.........:..:.|:  .|.|:
  Rat   363 LRILAERNRPHGQMLGEEAQEALQELENTCPLP--TTSTFSFASLLNYRNIW--KNLLI------ 417

  Fly   327 GTAQYVSALGGNIFISNAI------AAGVGIPGT-CLCALMTK---------------YLGRKKT 369
                    ||...||::||      ..|.|.|.. .||:|:..               ..||:..
  Rat   418 --------LGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGI 474

  Fly   370 LLLSNGCSAL-GLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLC 433
            ||||...:.: .|:||.......:|...|.:.:|||.:..:.....|...|:.||.||..|:||.
  Rat   475 LLLSMTLTGIASLVLLGLWDYLNDAAITTFSVLGLFSSQASAILSTLLAAEVIPTTVRGRGLGLI 539

  Fly   434 SMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLEDGE 492
            ..:|.:|.:..|.......:|.::..::....::|.:|..:.||||:...|||.|.|||
  Rat   540 MALGALGGLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	105/436 (24%)
Slc22a17	NP_803156.3	MFS_SLC22A17	170..583	CDD:341003	106/445 (24%)