Protein Alignment CG8654 and Slc22a21

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_008765965.1
• Gene: Slc22a21 / 303140
• RGDID: 1561735
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 154/548 - (28%)
• Similarity: 245/548 - (44%)
• Gaps: 81/548 - (14%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA------------------------- 61
            |.:.:.:|::..:|...||::.......|:..|..:||.|
  Rat     5 DELTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSAVFLTASPEHRCLVPDTVNLSSAWRNHSIPL 69

  Fly    62 ------PTPLSCKTENVT----------DPCSD---------ECSE-TEFDTSVFQSTIITEWNL 100
                  ..|..|:...:.          :|..|         .|.: .|:...||.|||:|||||
  Rat    70 EMKDGRQVPHKCRRYRLATIANFSALGLEPGEDVDLKQLELENCLDGWEYSKEVFLSTIVTEWNL 134

  Fly   101 TCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLF 165
            .|.....|.|:.|:..:|:|.||.:.|..:||:||:|.......|......:...|..:..:.|.
  Rat   135 VCNDAWKAPLTTSMFYVGVLLGSFISGQLSDRFGRKPVLFWTMGMHTGFSFLQVFSVNFEMFTLL 199

  Fly   166 RFLVAVATAGTMTTSFVLLMEIVGPKKREMVAIL-YQIPFNIGHASLALFAYFIREWRWFQFSIT 229
            ..||.:........:|||..||:....|.:.|.| ..|.|..|...|.|||||||:||....:||
  Rat   200 FALVGMGHISNYVAAFVLGTEILSKSIRIIFATLGICIFFAFGFMVLPLFAYFIRDWRMLLMAIT 264

  Fly   230 IFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKA--------PTETIRPEIEAAYGA 286
            :..::.....|.:|||||||.:.|::.::..|:.|.||.|..        |:||...:...|
  Rat   265 LPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSETTNLQDGNA--- 326

  Fly   287 LAARQPVKKGT----VVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAA 347
                    |.|    :.||.||..:||.||.....||.:.:.|:|.:.....|.|||:::..:.|
  Rat   327 --------KNTQSHHIYDLVRTRNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNGFLLA 383

  Fly   348 GVGIPGTCLCALMTKYLGRKKTLLLSNGCSALG---LILLACLSTQAEAVRVTCATIGLFGASIT 409
            .|.:|...|..|:.:::.|:.::.   |...||   |::|..:.:....:......:|.||.:..
  Rat   384 AVEVPAYVLAWLLLQHVTRRYSMA---GSLFLGGSVLLILQLVPSDLLYLSTALVMVGKFGITSA 445

  Fly   410 FPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTI 474
            :..||:|..||:|||||:.|||:.|...|:|||::|..|.|.||...:..::.|..:||..:.|.
  Rat   446 YSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRHLPYIVMGSLTILTAIITF 510

  Fly   475 FLPETRGTPLPETLEDGETFGRKKKDQA 502
            |.||:.|..||:|:::.:...|.::..|
  Rat   511 FFPESSGVSLPDTIDEMQKVKRIRRVSA 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	131/411 (32%)
Slc22a21	XP_008765965.1	2A0119	12..523	CDD:273328	150/524 (29%)