Protein Alignment CG8654 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 134/548 - (24%)
• Similarity: 231/548 - (42%)
• Gaps: 89/548 - (16%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA------------------------- 61
            |.|:..:||..|:|::...::.:....:..|.:...|.||
  Rat     4 DEILHHVGDRGRFQIWMIVVLNILSMVSSLHDVIENFTAAIPAHHCSVNLLDTSRSEISMAMNLT 68

  Fly    62 --------------PTPLSCK-------------------TENVTDPCSDECSETEFDTSVFQST 93
                          ..|..|:                   ||..|:||.|..:   :|.|||.||
  Rat    69 TEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETEPCLDGWT---YDHSVFTST 130

  Fly    94 IITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPY 158
            |:|||:|.|:.:.....:|:..:.|....:...|:.:||:||:|..:.|.....|.|......|.
  Rat   131 IVTEWDLVCDFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPLLMYCSLAYGILGTCCAFVPN 195

  Fly   159 YWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRW 223
            :..||:.|||.:.:.:.......:|::|....:....|.:|..:..:.|.|.|...||.:.:|..
  Rat   196 FSLYCVLRFLSSASASTVGMNCLILVLEETSVQWHATVIVLSGLFSSTGLAGLGGLAYVLSDWHL 260

  Fly   224 FQFSITI-FSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN-------KAPTETIRPEI 280
            .|.:..: :.|.|:::.| ||||.|||..|||.|:::|.|::||..|       ...||.:|.::
  Rat   261 IQLTSALPYFIFFILFCW-VPESARWLMITGKTDQALKELQRIASINGKKDIAQNLTTEDLRSKV 324

  Fly   281 EAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAI 345
            :.     .....||..::.|:...|.:|...:..::.........:|....|..||.|||::..:
  Rat   325 KE-----DVCSTVKHFSIKDIIINPMIRKIVLCYSSVLFAELFSIFGLLLDVHMLGKNIFVTQIL 384

  Fly   346 AAGVGIPGTCLCALMTKYLGRKK----TLLLSNGCSALGLILLACLSTQAEAVRVTCATI--GLF 404
            ...:.||...|...:.:.:.|:.    .|..:.||..:.:.    ||.....:|:....:  |.|
  Rat   385 LGVIDIPSKSLTYFILRNVRRRPLIAFLLFATGGCITITMF----LSEDMYVLRLAIFILGKGCF 445

  Fly   405 GASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIF-GIFSIL 468
            .|.|:....|.  .||.|..:||:..|:...|.|:.|:::.|.:....|.: :.|:|| |:..|:
  Rat   446 AAFISINTAYC--NELSPVPLRSTLNGIYISVARLASVLSALTLVTRKYFV-LLPMIFCGVLPIV 507

  Fly   469 AMLGTIFLPETRGTPLPETLEDGETFGR 496
            |.:...|||||...|:.:|::|.|...|
  Rat   508 ATINIYFLPETFNHPITDTIKDMEKRNR 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	107/409 (26%)
Slc22a22	NP_001013969.1	MFS_OAT	109..516	CDD:340932	113/422 (27%)