Protein Alignment CG8654 and Slc22a6

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_058920.1
• Gene: Slc22a6 / 29509
• RGDID: 69338
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 149/531 - (28%)
• Similarity: 247/531 - (46%)
• Gaps: 60/531 - (11%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCK-------------------- 68
            ::.|:|...|:||....:|:........|.....|.||..|..|:
  Rat     6 LLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKDGGLEAWLPLD 70

  Fly    69 -----------------------TE----NVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQ 106
                                   ||    .||:||.|   ...:|.|.|.|||:|||||.|..:.
  Rat    71 KQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCID---GWVYDNSTFPSTIVTEWNLVCSHRA 132

  Fly   107 LASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAV 171
            ...|:||:.|:|:|.|:::||..|||.|||...:.......::|.....:|.|..||:||.|..:
  Rat   133 FRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCVFRLLSGM 197

  Fly   172 ATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFV 236
            :.|........|.:|.:....|..|..|....:::|...||..||.:..||..|..:::...:..
  Rat   198 SLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLVVSVPFFIAF 262

  Fly   237 IYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKG--TVV 299
            ||.|...||.||..::|:||.:::.|:::|:.|....|..:..||....:|.....:.||  :.:
  Rat   263 IYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLRTSLQKELTLSKGQASAM 327

  Fly   300 DLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYL 364
            :|.|.|.:|...:.::..|......|||....:...|.::::...|...|.:|...:|.|:...:
  Rat   328 ELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSM 392

  Fly   365 GRK----KTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVV 425
            ||:    .:|||:..|    :::...:......:|.:.|.:|....:.:|..::||.|||:|||:
  Rat   393 GRRPAQMASLLLAGIC----ILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTVI 453

  Fly   426 RSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLED 490
            |.:|:|:.|.:.|:||||:||:...|.:...:...|||...::|...|..||||.|.|||:|::|
  Rat   454 RQTGLGMGSTMARVGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQD 518

  Fly   491 GETFGRKKKDQ 501
            .::..|.|::|
  Rat   519 LKSRSRGKQNQ 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	117/400 (29%)
Slc22a6	NP_058920.1	2A0119	11..515	CDD:273328	143/510 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..551		5/16 (31%)