Protein Alignment CG8654 and Slc22a19

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_775424.1
• Gene: Slc22a19 / 286961
• RGDID: 628885
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 154/561 - (27%)
• Similarity: 254/561 - (45%)
• Gaps: 107/561 - (19%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA-PT------------------------ 63
            :|:|||...|:|:.....||:|......||:...|.|| |:
  Rat     6 LITQIGCLGRFQILHLIFVLICFILVVPHTVLENFTAAIPSHRCWVPILDNNTMSDNNSRILSQD 70

  Fly    64 --------------PLSCK-------------------TENVTDPCSDECSETEFDTSVFQSTII 95
                          |..|:                   ||..|:||.|   ...:|.|.|.||.:
  Rat    71 DLLRISIPMDSNLRPEKCRRYIQPQWDLLHLNGTFSTVTEPDTEPCVD---GWVYDQSTFLSTTV 132

  Fly    96 TEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSPYY 159
            |:|:|.|.|:.|.|:::.|.|.||..|.::.|..:|::||: ..:||..:.| :|...|..:|.:
  Rat   133 TQWDLVCGSQTLNSVAKFIYMTGIFIGHLMGGHLSDKFGRK-FIVTCGLLTLAVTETSVAFAPTF 196

  Fly   160 WFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWF 224
            ..||..|||..::::...|.|.:|::|...||.:.||..|......||...|.:.|:.||.|:..
  Rat   197 LIYCSLRFLTGISSSCIRTNSALLILEWTSPKFQAMVMALIFSAGGIGQVLLGVLAFGIRNWQHL 261

  Fly   225 QFSITIFSIVFVIYI---WLVPESPRWLFTTGKLDKSIKILEKIAKCN-----------KAPTET 275
            |.::::  .||.:.|   || .||.|||..|.|..:.:|.|.|:|..|           :....|
  Rat   262 QLAMSV--PVFFLLIPTRWL-SESARWLIITNKPQEGLKELIKVAHINGIKNSRDVLTLEVVKTT 323

  Fly   276 IRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTA------QYVSA 334
            ::.|:|||        ..|...:| |||||.:|.:...::   .|.|:....|.      ||:|
  Rat   324 MKDELEAA--------ETKPSPLV-LFRTPNLRKRICLLS---FVRCVSLISTVGLLINLQYLS- 375

  Fly   335 LGGNIFISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCA 399
              ..:|:...:...|..|...|......|:||:.|.::......:.::.:..|:.:.:..|:..|
  Rat   376 --NKVFLLQCLYGVVCTPANLLGNFSMNYMGRRTTQIIFMSVMGISILSITFLTQEMQIPRLVLA 438

  Fly   400 TIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGI 464
            ::|...:|.:..:..:...||.|||:|::.:|:..:.|..|:.::||::.|..|...:..:|:|:
  Rat   439 SLGGAISSASLTSTAVLSNELVPTVIRATALGVIGIFGSAGAALSPLLMILMTYSASLPWIIYGV 503

  Fly   465 FSILAMLGTIFLPETRGTPLPETLEDGETFGRK-----KKD 500
            ..||:.|..:.|||||..|||::::|.|. .||     |||
  Rat   504 LPILSSLVVLLLPETRNQPLPDSIQDVEN-KRKSSREVKKD 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	116/415 (28%)
Slc22a19	NP_775424.1	MFS	109..506	CDD:475125	119/418 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..551		8/21 (38%)