DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and Slc22a29

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_766364.1	Gene:	Slc22a29 / 236293	MGIID:	3605624	Length:	551	Species:	Mus musculus

Alignment Length:	466	Identity:	133/466 - (28%)
Similarity:	225/466 - (48%)	Gaps:	40/466 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WHTLGHIFLAAPTPLSCKTENVTDPCSDECSE-TEFDTSVFQSTIITEWNLTCESKQLASLSQSI 114
            ||.| |        |:....||::|.::.|.: ..:|.|.|.|||:|||:|.|||:.|.|:::..
Mouse    96 WHLL-H--------LNGTFSNVSEPDTEPCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVTKFS 151

  Fly   115 VMLGILFGSILFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSPYYWFYCLFRFLVAVATAGTMT 178
            .|:|:..|.|:.|..:||:||: ..|||..:|. ||...|..:|.::.||..|||..::......
Mouse   152 FMIGLFIGGIICGHLSDRFGRK-FILTCALLQFAITETCVAFAPSFFIYCSLRFLAGMSVEPISV 215

  Fly   179 TSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVP 243
            .|.:|::|...||...|:|:|.....|||...||..|:..|.|...|.:::.....|:|....:.
Mouse   216 NSHLLMLEWTSPKFLAMMAVLSSCAPNIGFMILAGLAFLFRIWHHLQLTMSAPIFFFLILTRWLS 280

  Fly   244 ESPRWLFTTGKLDKSIKILEKIAKCN----------KAPTETIRPEIEAAYGALAARQPVKKGTV 298
            ||.|||....|..|.:|.|.|:|..|          :....:::.|:|||         ..|.::
Mouse   281 ESARWLILINKPQKGLKELRKVAHMNGMKNSGDLTMEIVRTSMKAELEAA---------KTKPSL 336

  Fly   299 VDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNI----FISNAIAAGVGIPGTCLCAL 359
            .|||.|..:|.:...::...|...:...|.|.::..|..||    |:.:|:|..|.:.|    ..
Mouse   337 RDLFHTSILRKRICVLSFIRLFFTVSIIGLAVHLQHLSSNIILLQFLISALAILVSVIG----PF 397

  Fly   360 MTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTV 424
            :..::||:.|.|:......:.:::...:..:.:.:|:..||:....:|:.....:|:..||.||.
Mouse   398 VLNHIGRRITYLVLMSLRGIFIMIAVFVPQEMQTLRIIMATLAGGISSLCVGVSHLHTNELLPTT 462

  Fly   425 VRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLE 489
            :|::.:|:....|..|..::||.:.:|.|...:..:.:|.|||........||||:..|||::..
Mouse   463 LRATALGVIGFFGNSGLFLSPLFMLVATYYANLPWIFYGGFSIFNAFTVFLLPETKNQPLPDSTH 527

  Fly   490 D-GETFGRKKK 499
            | |..:...:|
Mouse   528 DVGNDWKESRK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	121/416 (29%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	113/404 (28%)
Slc22a29	NP_766364.1	MFS_OAT	109..515	CDD:340932	116/419 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464838at2759
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020