Protein Alignment CG8654 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 593
• Identity: 137/593 - (23%)
• Similarity: 237/593 - (39%)
• Gaps: 130/593 - (21%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA------------------------- 61
            |.|:..:||..|:|:....::.:.......|.:...|.||
Mouse     4 DEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMNLTT 68

  Fly    62 -------------PTPLSCK-------------------TENVTDPCSDECSETEFDTSVFQSTI 94
                         ..|..|:                   ||..|:||.|..:   :|.|||.|||
Mouse    69 EDLMKVSIPMGPNQKPEQCRRFRYTQWQFLDSNISTFNSTELETEPCLDGWT---YDHSVFTSTI 130

  Fly    95 ITE---------------------------------WNLTCESKQLASLSQSIVMLGILFGSILF 126
            :||                                 |:|.|:.:.....:|:..:.|.|....|.
Mouse   131 VTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKYYAQATSLAGHLVSCPLS 195

  Fly   127 GMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPK 191
            |:.:||:||:|..:.|.......|.....:|.:..||:.|||::...:..:..|.:|::|....:
Mouse   196 GIISDRFGRKPLLMYCSLAYGAVGTYCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEEASVQ 260

  Fly   192 KREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITI-FSIVFVIYIWLVPESPRWLFTTGKL 255
            ....:.:|..:..:||...|...||.|.:|...|.:..: |.|.||::.| ||||.|||..|||.
Mouse   261 WHPTIIVLSGLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFIFFVLFCW-VPESVRWLIITGKT 324

  Fly   256 DKSIKILEKIAKCN-------KAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIF 313
            |::.|.|::||..|       ...||.:|.:::....:..     |...:.|:|..|.  |:.|.
Mouse   325 DQAWKELQRIASINGKKGIAQNLTTEDLRSKLKKDVNSTG-----KLFRIKDIFINPL--IRKIV 382

  Fly   314 MANNWLVVCMV--YYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRKKT---LLLS 373
            ::|:.|:...:  :.|....|..||.|:|::......:.:|...|.....:.:.|:..   |||:
Mouse   383 LSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYFTIRNVSRRPLIAFLLLT 447

  Fly   374 NG-CSALGLILLACLSTQAEAVRVTCATI--GLFGASITFPNVYLYGGELFPTVVRSSGVGLCSM 435
            .| |..:.:.    :|.:...:|.....:  |.|.|.......|:  .||.|..:||:..|:...
Mouse   448 TGSCITITIF----ISEEMYVLRTIIFILGKGCFAAFTCISTTYI--NELSPVELRSTLNGVFLA 506

  Fly   436 VGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLEDGETFGR---- 496
            |.|:..:::.|.:....|.:::..:::|:..|:|.:..:|||||...|..:.::|.|...|
Mouse   507 VVRLAGVLSALTLATRKYFVYLPMILYGVLPIVATISILFLPETFNLPHTDIIKDMEKRKRLMSK 571

  Fly   497 ---KKKDQ 501
               ||:.|
Mouse   572 NISKKEGQ 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	108/443 (24%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	114/456 (25%)