Protein Alignment CG8654 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 453
• Identity: 151/453 - (33%)
• Similarity: 229/453 - (50%)
• Gaps: 47/453 - (10%)

  Fly    69 TENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRY 133
            ::..|:||.|   ...:|.|.|:|||:|.|:|.|.|:.|..::|||.:.|||.|:.:.|..:||:
Mouse   109 SDAATEPCED---GWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRF 170

  Fly   134 GRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAI 198
            |||........:..::|......|.:..|||||||:|.|.||.|..:..||||....:...:|..
Mouse   171 GRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMT 235

  Fly   199 LYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILE 263
            |..:.|:.|.......||.:|.||..|.:::....:|.:|.|.:|||.|||.|.||||:.::.|:
Mouse   236 LNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQ 300

  Fly   264 KIAKCN--KAPTETIRPEI-EAAYGALAARQPVKKG-TVVDLFRTPYMRIKTIFMANNWLVVCMV 324
            ::|..|  ||..:|:..|: .:|.....:|.  |.| ::..|..||.:|.:||.....|......
Mouse   301 RVAAVNRRKAEGDTLTMEVLRSAMEEEPSRD--KAGASLGTLLHTPGLRHRTIISMLCWFAFGFT 363

  Fly   325 YYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRK---------------KTLLLSN 374
            :||.|..:.|||.|||:..|:...|..|......|:...|||:               ..:|:.:
Mouse   364 FYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLCILSNILVPH 428

  Fly   375 GC----SALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSM 435
            |.    |||.::.|.||..     ..||.||              :..||||||:|.:.||||.:
Mouse   429 GMGVLRSALAVLGLGCLGG-----AFTCITI--------------FSSELFPTVIRMTAVGLCQV 474

  Fly   436 VGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLEDGETFGRKK 498
            ..|.|:::.||:..|..||.|:..|::|:..:|:.|..:.||||:..|||:|::|.:....||
Mouse   475 AARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQDIQKQSVKK 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	136/417 (33%)
Slc22a12	NP_033229.3	MFS_OAT	109..516	CDD:340932	140/430 (33%)