Protein Alignment CG8654 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 536
• Identity: 160/536 - (29%)
• Similarity: 256/536 - (47%)
• Gaps: 86/536 - (16%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA---------------------PTPL 65
            |.:.:.:|::..:|...||::.......|::.:..:|||.                     ..||
Mouse     5 DEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPL 69

  Fly    66 SCKT-ENVTDPC----------------------------SDECSE-TEFDTSVFQSTIITEWNL 100
            ..|. ..|...|                            .:.|.: .|:|..||.|||:|||:|
Mouse    70 ETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDL 134

  Fly   101 TCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPA-FLTCCFMQLITG---LIVCVSPYYWF 161
            .|:....|.|:.|:..:|:|.||.:.|..:||:||:.. |||   |.:.||   |.|....:..|
Mouse   135 VCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLT---MGMQTGFSFLQVFSVNFEMF 196

  Fly   162 YCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREM-----VAILYQIPFNIGHASLALFAYFIREW 221
            ..|| .||.:........:|||..||:....|.:     |.|.|...|.:    |.|||||||:|
Mouse   197 TVLF-VLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMV----LPLFAYFIRDW 256

  Fly   222 RWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAPTETIRP-EIEAA 283
            |....::|:..::.....|.:|||||||.:.|::.::..|:.|.||.|  .||:....| |::
Mouse   257 RMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQ-- 319

  Fly   284 YGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAG 348
              .|.:.:| :...:.||.||..:|:.||.....||.:.:.|:|.:.....|.|:|:::..:.|.
Mouse   320 --DLNSTKP-QLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAA 381

  Fly   349 VGIPGTCLCALMTKYLGRKKTLLLSNGCSAL---GLILLACLSTQAEAVRVTCA--TIGLFGASI 408
            |.:|...|..|:.:||.|:.::     .:||   |.:||......:|...::.|  .:|.||.:.
Mouse   382 VEVPAYVLAWLLLQYLPRRYSI-----SAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITS 441

  Fly   409 TFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGT 473
            .:..||:|..||:|||||:.|||:.|...|:|||::|..|.|.||..::..::.|..:||..:.|
Mouse   442 AYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT 506

  Fly   474 IFLPETRGTPLPETLE 489
            :|.||:.|.|||:|::
Mouse   507 LFFPESFGVPLPDTID 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	138/412 (33%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	158/525 (30%)