Protein Alignment CG8654 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 308
• Identity: 60/308 - (19%)
• Similarity: 93/308 - (30%)
• Gaps: 140/308 - (45%)

  Fly   230 FE-RWQ-----------WRCGHRARRLELRAYGGQTINGTFYLSLSICFALISNVNMIHATHAIA 282
            || ||:           ::|.|..:|..:|:                  .||.:.    |||..|
Mouse   340 FELRWKFINHVRAHVKHYKCSHCDKRFTMRS------------------CLIRHA----ATHTGA 382

  Fly   283 ----CFPSPHHKIVGSDDIEEKEAEMSFIHFQSTC--HLALDSCRDDQVCSSALKTV--LMHCDQ 339
                |            ||..|    ||: ||::.  |..|.:......|.:..|..  .....:
Mouse   383 QLFKC------------DICSK----SFV-FQASLEKHKHLHTAEKTVTCPNCQKVFPGTRSFGR 430

  Fly   340 HRCNRNACMESLQSFYKSIHDDLSLDIAFCLCRKTPNRHDSCMIAQEKLHPVCAQ--RPPESLSQ 402
            |||      .::::.|                        :|        |||.:  :..:::..
Mouse   431 HRC------RAVETLY------------------------NC--------PVCDKQFKIKQNMLD 457

  Fly   403 QQSSSTGNGIAYNAPPACHAVAELCREDEDCRARL---------EVFEQSCAVDSVTKKCAGKTS 458
            .|:..||.      .|.|   .|:|.|...|...|         :.:|.||.:      |..:.|
Mouse   458 HQTLHTGE------KPYC---CEICGEFYSCERYLKNHQKSHIEKTYEFSCEI------CEKRFS 507

  Fly   459 ACR--QAMLGILGTPLRTTC-ACQ--------------GSDMQQLYDC 489
            |.:  ||.:.:.....|.|| .|.              |....:||.|
Mouse   508 ARKHLQAHMLVHTREKRYTCDVCDKKFATSGNLNRHKAGHTGVKLYGC 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	55/280 (20%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	52/276 (19%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288