Protein Alignment CG8654 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 144/551 - (26%)
• Similarity: 246/551 - (44%)
• Gaps: 93/551 - (16%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA-PT------------------------ 63
            :::|:|...|:|:.....:|:.......|:|...|.|. |.
  Rat     6 LLNQVGSLGRFQILQMTFILIFNIIISPHSLLENFTAVIPNHRCWVPILDNDTVSGNDNGNLSQD 70

  Fly    64 --------------PLSCK-------------------TENVTDPCSDECSETEFDTSVFQSTII 95
                          |..|:                   ||..|:||.|   ...:|.|.|.||||
  Rat    71 DLLRVSIPLDSDLRPEKCRRFVQPQWDLLHLNGTFSSVTEPDTEPCVD---GWVYDQSTFLSTII 132

  Fly    96 TEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSPYY 159
            |||:|.|||:.|.|:::.:.:.|||.|:||:|...||:||| ..|.|..:|: :|......:|.:
  Rat   133 TEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRR-LILICASLQMAVTETCAAFAPTF 196

  Fly   160 WFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWF 224
            ..||..|||..::.:..:|.|.:|::|...||.:.:...|......||...||..|:.:|.|...
  Rat   197 LIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAGAIGQTVLAGLAFTVRNWHHL 261

  Fly   225 QFSITIFSIVFVIYIWLVP-----ESPRWLFTTGKLDKSIKILEKIAKCNKAPTET--------- 275
            ..::::     .|:..|||     ||.|||..|.||.|.:|.|.|:|..|.....|
  Rat   262 HLAMSV-----PIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTIEVVR 321

  Fly   276 --IRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGN 338
              ::.|:||:.         .|.::.||||||.:|.:...::....||.:...|.......|..|
  Rat   322 TIMKEELEASQ---------TKSSLWDLFRTPNLRKRICLLSLVRFVVWLSVIGLLINFQHLRIN 377

  Fly   339 IFISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGL 403
            :|:...:...:.||...:...:..:|||:.:.|.......:.::.:..:..:.:.:|:..||.|.
  Rat   378 VFLLQCLLGIITIPANLVGIFLVNHLGRRISQLFIISLFGISILAIIFVPQEMQILRMVLATFGG 442

  Fly   404 FGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSIL 468
            ..:.::..:..::..||.||::|::.:|:..:.|..|:.::||.:.|..|...:..:|:|:.|.|
  Rat   443 VFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILRTYSDSLPWIIYGVLSFL 507

  Fly   469 AMLGTIFLPETRGTPLPETLEDGETFGRKKK 499
            ..|..:.||||:..|||::::|.|..||..:
  Rat   508 GGLVVLLLPETKNQPLPDSIQDVENEGRASR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	115/411 (28%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	118/414 (29%)