DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8654 and K11D9.3

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_499382.1	Gene:	K11D9.3 / 176510	WormBaseID:	WBGene00010772	Length:	480	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	126/523 - (24%)
Similarity:	208/523 - (39%)	Gaps:	125/523 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPT--PL--------SCKTENVTDPCS--DEC-S 81
            |..|:.|   .::|..:|.        ||.|:..  |:        :|.....|..||  :.| |
Worm     4 DINRFHL---LVLLTWQFS--------IFFASQQIFPIFSNYVPQWTCGNGEPTSDCSVYESCKS 57

  Fly    82 ETEFDTSVFQSTIITEWNLTC-ESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFM 145
            ...|....|:|..: |::..| :|..|.||...|...|:|.|:..||..:|..||:|..:....:
Worm    58 NLTFVNVAFKSAAM-EYDWICGKSAYLKSLFSQIQFAGVLCGTFSFGAVSDVVGRKPVAVFALSL 121

  Fly   146 QLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHAS 210
            .::...:..::|.|......||.:.::..||:......:||::.|::|..:...    ||.|.|.
Worm   122 GILMNFVTGLAPNYQVLLGIRFFLGLSVGGTLVVVCTFVMEMLLPQQRMALRAF----FNWGVAR 182

  Fly   211 L--ALFAYFIREWRWFQFSITIFSI-VFVIYIWLVPESPRWLFTTGKLD---KSIKILEKIAKCN 269
            |  .|.|..:.|||....:..:.:: ..:|.:::.||||.||...|:||   ||.|.:.|:|...
Worm   183 LMMTLIAMALPEWRMSSIACAVAALPALIIIVFVFPESPTWLHNKGRLDEMKKSEKHIAKMAGVP 247

  Fly   270 KAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSA 334
            ..|.|..|.|              ...||:::.:|..:..:...:.:.|.|..:..|.|....:.
Worm   248 YVPIEHKRIE--------------HSKTVMEMLQTKGLMSRLFVLWSMWFVASICGYATDLNSNT 298

  Fly   335 LGGNIFISN---AIAAGVG----------IPG-------------TCLCALMTKYLGRKKTLLLS 373
            :.|::|::.   :|...|.          :|.             .|:|.|:.       |.:..
Worm   299 ISGDLFVNQILFSILIAVSKMILVVFDTHVPSFRRRTLHQGAQLVVCICFLIL-------TFMTF 356

  Fly   374 NGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGR 438
            ||.:.|..:::              ..||......|:...||...|...|..|:|..|.||:|.|
Worm   357 NGYTGLAFLIV--------------NLIGTVFIEYTWDACYLCAVESMETACRASATGTCSLVAR 407

  Fly   439 IGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTI-------FLPETR---------------G 481
            ||:|:||:   |....||..|   .::..:.:||||       ||.||:               |
Worm   408 IGAILAPM---LNYANLWWPP---SVYLTVVLLGTINLIISYFFLVETKNVNLDNVHIDPSSEEG 466

  Fly   482 TPL 484
            ||:
Worm   467 TPM 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	111/455 (24%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	104/429 (24%)
K11D9.3	NP_499382.1	2A0119	<66..454	CDD:273328	107/433 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48025
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920