Protein Alignment CG8654 and lelo-2

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001408283.1
• Gene: lelo-2 / 175300
• WormBaseID: WBGene00022348
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 159/539 - (29%)
• Similarity: 254/539 - (47%)
• Gaps: 81/539 - (15%)

  Fly    19 KTGDPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTP------------------- 64
            |..|.:.:.:|:..:||...||:|.|.......|.|...|.:..||
 Worm     2 KFDDFLFTYLGEMGKYQKIQFFLVCLPTIVVSMHALSWTFASVDTPYRCRLPSDLPEKEPYYTTL 66

  Fly    65 -----------------------LSCKTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQ 106
                                   ::|..:..|.|.::.|.|..||.|..:.|.:..|.:||:...
 Worm    67 LNFTKCTNDADANVPISEYGKPGVTCHYDRCTLPDNETCHEHIFDHSKVEYTAVQRWEITCDRSW 131

  Fly   107 LASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAV 171
            :.:..|:...:|.:.||..|||..||.||:..|.....:|:....::.::||:|.|.|.|.....
 Worm   132 IKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQITCAYLIAIAPYWWLYALARAGTGF 196

  Fly   172 ATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFV 236
            :..|....:.|:.||:||||.|::.:::..:.|.:|...|.:.|.:...::.....|...:::|:
 Worm   197 SHPGIFVIAVVIGMELVGPKYRKLASVITGLFFALGQIFLGIEAIYFTNYQILHVVIASPALLFL 261

  Fly   237 IYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPE-------IEAAYGALAARQPVK 294
            .|.||||||.|||.:..:..::.::|:|.|..|    .|:.||       .....|..|...|.|
 Worm   262 SYWWLVPESARWLVSQKRYKEADEVLQKAASVN----GTVLPENWWEQLDDSTTGGGGAPGAPTK 322

  Fly   295 KGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCAL 359
            |.|..||||||.:|.:|:.:...|.|:.|||||.|...:.|||:|:::...||.|.||...:..|
 Worm   323 KLTGADLFRTPELRKRTLVVFFLWPVISMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYL 387

  Fly   360 MTKYLGRKKTLLLSNGCSALGLILLACLST---QAEAVRVTCA--TIGLFGASIT--FPNVYLYG 417
            :...:||:  |:|:.|....|    |||..   ..:.|::..|  .:.....|||  :..:|.|.
 Worm   388 LIDRIGRR--LILAGGLFIAG----ACLLVNWLMGDNVQLWMAITQMAFTKGSITGVYAAIYTYS 446

  Fly   418 GELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAP--------LIFGIFSILAMLGT- 473
            .||||||:|::.:|.||.:.|:|:|.|..|      .:|:|.        :.||..::||.:.|
 Worm   447 PELFPTVIRNTAMGFCSTIARVGAIAASYI------SMWIAEQFGKVFMIIPFGCMAVLAAVMTL 505

  Fly   474 IFLPETRGTPLPETLEDGE 492
            :|||||.|.||||::|:.|
 Worm   506 LFLPETMGKPLPESIEEIE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	130/417 (31%)
lelo-2	NP_001408283.1	MFS_SLC22	107..508	CDD:340875	129/416 (31%)