Protein Alignment CG8654 and Slc22a27

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_017173565.1
• Gene: Slc22a27 / 171405
• MGIID: 3042283
• Length: 576
• Species: Mus musculus
• Alignment Length: 471
• Identity: 138/471 - (29%)
• Similarity: 229/471 - (48%)
• Gaps: 44/471 - (9%)

  Fly    51 WHTLGHIFLAAPTPLSCKTENVTDPCSDECSE-TEFDTSVFQSTIITEWNLTCESKQLASLSQSI 114
            ||.| |        |:....||::|.::.|.: ..:|.|.|.|||:|||:|.|||:.|.|:::..
Mouse   121 WHLL-H--------LNGTFSNVSEPDTEPCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVTKFS 176

  Fly   115 VMLGILFGSILFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSPYYWFYCLFRFLVAVATAGTMT 178
            .|:|:..|.|:.|..:||.||: ..|||..:|. ||...|..:|.::.||..|||..::....:.
Mouse   177 FMIGLFIGGIICGHLSDRLGRK-FILTCALLQFAITETCVAFAPSFFIYCSLRFLAGLSVEPILV 240

  Fly   179 TSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVP 243
            .|.:|::|...||...|:|.|.....|||:...|..|:..|.|...|.::::....|:|....:.
Mouse   241 NSHLLMLEWTSPKFLTMMAALLSCAPNIGYMISAGLAFLFRIWHHLQLTMSVPIFFFLILTRWLS 305

  Fly   244 ESPRWLFTTGKLDKSIKILEKIAKCN----------KAPTETIRPEIEAAYGALAARQPVKKGTV 298
            ||.|||..|.|..|.:|.|.|:|..|          :....:::.|:|||         ..|.::
Mouse   306 ESARWLIVTNKPQKGLKELRKVAHMNGMKNSGDLTMEIVRTSMKAELEAA---------KTKPSL 361

  Fly   299 VDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNI----FISNAIAAGVGIPGTCLCAL 359
            .|||.|..:|.:...::...|...:..:|.|.::..|..||    |:.:|:|..|.:.|    ..
Mouse   362 RDLFHTSILRKRICVLSFMRLFFTVSIFGLAVHLQHLSSNIILLQFLISALAILVSVIG----PF 422

  Fly   360 MTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTV 424
            :..::||:.|.|:......:.:::...:..:.:.:|:..||:....:|:......|:..||.||.
Mouse   423 VLNHIGRRITYLVLMSLRGIFILIAVFVPQEMQTLRIIMATLAEGISSLCVGVSRLHTNELLPTT 487

  Fly   425 VRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLE 489
            :|::.||:....|..||.::||.:.||.|...:..:.:|.|||........||||:..|||::..
Mouse   488 LRATAVGVIGFFGNSGSFLSPLFMLLATYYANMPWIFYGGFSIFNAFTVFLLPETKNQPLPDSTH 552

  Fly   490 D-----GETFGRKKKD 500
            |     .|:...||:|
Mouse   553 DVGNDWKESRKGKKED 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	117/410 (29%)
Slc22a27	XP_017173565.1	MFS_OAT	134..540	CDD:340932	119/419 (28%)