DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and Ust5r

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	449	Identity:	125/449 - (27%)
Similarity:	213/449 - (47%)	Gaps:	24/449 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WHTLGHIFLAAPTPLSCKTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIV 115
            ||     .|......|..||..|:||.|   ...:|.|.|.||.:|||:|.|||:.|.|:::...
  Rat    96 WH-----LLDLNDTFSSVTEADTEPCVD---GWVYDRSNFHSTTVTEWDLVCESQVLNSVTKFSF 152

  Fly   116 MLGILFGSILFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSPYYWFYCLFRFLVAVATAGTMTT 179
            |:|...|.|:.|..:||:||: ..|.|..:|: ||...|..:..::.||..|||..:.....:..
  Rat   153 MIGAFIGGIVNGPLSDRFGRK-FVLKCALLQMAITETCVGFASNFFIYCSLRFLAGMTFEPILVN 216

  Fly   180 SFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPE 244
            |.:|:.|....|...|::::.....:.|...||..|:..:.|...|.::::....|:|....:.|
  Rat   217 SNLLMFEWTSHKFLAMMSVIAPCAGSFGSMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSE 281

  Fly   245 SPRWLFTTGKLDKSIKILEKIAKCN-------KAPTETIRPEIEAAYGALAARQPVKKGTVVDLF 302
            |.|||..|.|..|.:|.|.|:|..|       ....|.:|..::....|..||...:     |||
  Rat   282 SARWLIVTNKPQKGLKELRKVAHMNGMKNSGDNLTMEVVRTSMKRELEAAKARPSPR-----DLF 341

  Fly   303 RTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRK 367
            .||.:|.:...|:...::..:..:|.:.::..|..||.:...:.:...:..:.:...:...:||:
  Rat   342 HTPILRKRICAMSFMRILFMLSIFGMSLHLQHLSSNIMLLQFVVSASSLLFSVIGPYVFNRMGRR 406

  Fly   368 KTLLLSNGCSALGLILLACLSTQAEAVRVTCATI-GLFGASITFPNVYLYGGELFPTVVRSSGVG 431
            .|.::......:.::....:..:.:.:|:|..|: |.|.| ::|....|:..||.||.:|::.:|
  Rat   407 ITQMVVMTLRGICILTAVFVPQEMQILRITVVTLAGAFSA-LSFGVNRLHTNELLPTTLRATAIG 470

  Fly   432 LCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLED 490
            :..|.|..|..:|||.:.||:|...:..:.:|.||||.......||||:..|||:.:.|
  Rat   471 VIGMFGNSGFFLAPLFMILASYSPNLPWIFYGGFSILNGFTVFLLPETKNQPLPDCIHD 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	114/410 (28%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	106/398 (27%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	113/416 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464838at2759
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020