DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and UST4r

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	130/466 - (27%)
Similarity:	214/466 - (45%)	Gaps:	36/466 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WHTLGHIFLAAPTPLSCKTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIV 115
            ||     .|......|..||..|:||.|   ...:|.|.|.||.:|||||.|||:.|.|:::...
  Rat    96 WH-----LLDLNDTFSSITEPDTEPCVD---GWVYDRSNFHSTTVTEWNLVCESQALNSVTKLSF 152

  Fly   116 MLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTS 180
            |:|...|.|:.|:.:||:||:...........||......:|..:.||..|||..::........
  Rat   153 MIGAFIGGIVNGLLSDRFGRKFILKYALLQMAITETCAGFAPNLFIYCSLRFLAGMSLEPITVNI 217

  Fly   181 FVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPES 245
            .:|:.|...||...||.:|.....:.|...||..|:..:.|...|.::::....|:|....:.||
  Rat   218 NLLMFEWTSPKFLTMVTVLGSCAGSFGGMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSES 282

  Fly   246 PRWLFTTGKLDKSIKILEKIAKCN-----------KAPTETIRPEIEAAYGALAARQPVKKGTVV 299
            .|||....|..|.:|.|:|:|..|           :....:::.|:|||....:.|
  Rat   283 ARWLIVINKPQKGLKELKKVAHINGMKKSGDNITMEVVRTSMKKELEAAKMRPSPR--------- 338

  Fly   300 DLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYL 364
            |||.||.:|.:...::...|:..:...|.|.::..|..||.:...:.:...|..:.:...:..::
  Rat   339 DLFHTPILRKQIYILSFIRLLFILSGVGVAIHLQHLSNNIELLQILISVSSILFSVIGHFVLNHI 403

  Fly   365 GRKKT---LLLSNGCSALGLILLACLSTQ-AEAVRVTCATIGLFGASITFPNVYLYGGELFPTVV 425
            ||:.|   ::...|.|    ||.|..:.| .|.:|...|.:....|::::....|:..||.||.:
  Rat   404 GRRITQMVIMFLRGIS----ILTAIFAPQEMETLRFIMAMMAEGLAALSYAANSLHANELLPTTL 464

  Fly   426 RSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLED 490
            |::..|:..|.|.||..:|||.:.||:|...:..:.:|.|:||:....:.||||:..|||:...|
  Rat   465 RATARGVIGMFGNIGFFLAPLCMMLASYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPDCTHD 529

  Fly   491 GETFGRKKKDQ 501
            .|...::.:.:
  Rat   530 VENDWKESRQE 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	118/416 (28%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	110/404 (27%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	117/422 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010