Protein Alignment CG8654 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 108/436 - (24%)
• Similarity: 186/436 - (42%)
• Gaps: 51/436 - (11%)

  Fly    98 WNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFY 162
            |||.|.......|.|...:||.|.|.::.|...||:|||..|:....:....|....::..:...
Human     9 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAASFPTL 73

  Fly   163 CLFRFLVAVATAGTMTTSFVLLMEIVGPKKR---EMVAILYQIPFNIGHASLALFAYFIREWRWF 224
            .:.|.|.....||.:...::..:|:..|..|   .|.|.|:.:   :|...|...|..:::||..
Human    74 LVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSV---VGTLLLPGLAALVQDWRLL 135

  Fly   225 QFSITIFSIVFVIYIW----LVPESPRWLFTTGKLDKSIKILEKIAKCN-KAPTETIRPE--IEA 282
            |....:.|.:.::: |    |.||||.||..||::.::.|||.:.|:.: ..|.::...|  :..
Human   136 QGLGALMSGLLLLF-WGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEENSLAT 199

  Fly   283 AYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNI-------- 339
            ....|:||.|..:      :.:|...::|.....|.|::        .:.|.:||.|
Human   200 ELTMLSARSPQPR------YHSPLGLLRTRVTWRNGLIL--------GFSSLVGGGIRASFRRSL 250

  Fly   340 -------FISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSAL-GLILLACLSTQAEAVRV 396
                   ::...:.||:.........|.....||:..|||....:.| .|:|||..........:
Human   251 APQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQYLPGWTVL 315

  Fly   397 TCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLI 461
            ..:.:||..:........|:..|:||||:|.:|:||....|.:|....||.......|.::..::
Human   316 FLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVV 380

  Fly   462 FGIFSILAMLGTIFLPETRGTPLPETLEDGETF-------GRKKKD 500
            |...::||:|..:.|||:|...||::|:|.:..       ||.::|
Human   381 FASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRSPLLRGRPRQD 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	103/414 (25%)
		MFS	87..477	CDD:119392	97/404 (24%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	94/391 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010