Protein Alignment CG8654 and SVOPL

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001132928.1
• Gene: SVOPL / 136306
• HGNCID: 27034
• Length: 492
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 139/561 - (24%)
• Similarity: 224/561 - (39%)
• Gaps: 146/561 - (26%)

  Fly     1 MADRPQDP-------------KAPKPLKPVTKTGDPIISQIGDFRRYQLFFFFIVLLCKFGTGWH 52
            ||.:|.:|             ..|:..:|.|.|.:..:..|| |.|:.:..|.|:    ..||..
Human     1 MATKPTEPVTILSLRKLSLGTAEPQVKEPKTFTVEDAVETIG-FGRFHIALFLIM----GSTGVV 60

  Fly    53 TLGHIFLAAPTPLSCKTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVML 117
            ....|.|.|                           |....|..||.|  |:.|:| |..::|..
Human    61 EAMEIMLIA---------------------------VVSPVIRCEWQL--ENWQVA-LVTTMVFF 95

  Fly   118 GILFGSILFGMFADRYGRRP----AFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMT 178
            |.:..|||||:.||||||..    :||...:..|:|..    :|.|.::...|.:|....:| .:
Human    96 GYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSF----APSYIWFVFLRTMVGCGVSG-HS 155

  Fly   179 TSFVLLMEIVGPKKREMVAILYQIPFN-----------IGHASLALFAYFIREWRWFQFSITIFS 232
            ...::..|.:..|.|.     |.:|.:           ||.||:.:...   .|||.....:|..
Human   156 QGLIIKTEFLPTKYRG-----YMLPLSQVFWLAGSLLIIGLASVIIPTI---GWRWLIRVASIPG 212

  Fly   233 IVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPV--KK 295
            |:.::....:|||.|:..:||....::..||::||.|:    ::.||     |.|.  :||  |:
Human   213 IILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNR----SVMPE-----GKLV--EPVLEKR 266

  Fly   296 GTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSA--LGGNIFISNAIAAGVGIPG----- 353
            |...||....|:| .|:.:...||.:...|||.. ..||  |..::...:...:.|.:.|
Human   267 GRFADLLDAKYLR-TTLQIWVIWLGISFAYYGVI-LASAELLERDLVCGSKSDSAVVVTGGDSGE 329

  Fly   354 ---TCLCALMT-------------------------KYLGRKKTLLLSNGCSALGLILLACLSTQ 390
               .|.|.:..                         .:|||:.:|.::.||:||..:||
Human   330 SQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLL------ 388

  Fly   391 AEAVRVTCATIGLFG--------ASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLI 447
                .:..::.||.|        .:..|..||:|..|::||.:|:.|:|....:.|||::|||.|
Human   389 ----NICTSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFI 449

  Fly   448 VD-LAAYGLWVAPLIFGIFSILAMLGTIFLP-ETRGTPLPE 486
            .. |.:..:..|..:|....::..:....|| ||:|..|.:
Human   450 SQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQ 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	114/455 (25%)
SVOPL	NP_001132928.1	MFS_SVOPL	49..480	CDD:341000	121/500 (24%)