Protein Alignment CG8654 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 161/602 - (26%)
• Similarity: 244/602 - (40%)
• Gaps: 146/602 - (24%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA------------------------- 61
            :.::.|:|.|..:||....::.|.:.....|.|..|||||
Human     4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWLEAH 68

  Fly    62 ------PTPLSC------------------------KTENVTDPCSDECSETEFDTSVFQSTIIT 96
                  .|..||                        :.|..|.|||   ...|:|.|.|.|||.|
Human    69 LPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCS---QGWEYDHSEFSSTIAT 130

  Fly    97 -------------------------------------------------------------EWNL 100
                                                                         ||:|
Human   131 ESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRESLGGLLSGMEWDL 195

  Fly   101 TCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLF 165
            .||.|.|...:.:....|:|.|::.||..:||:|||...|......|:.||....|..|..:.:.
Human   196 VCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAIT 260

  Fly   166 RFLVAVATAGTMTTSFVLL--------MEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWR 222
            |.|...|.||     |.::        :|.:..:.|.:..:|....:..|...|||..|.||:||
Human   261 RTLTGSALAG-----FTIIVMPLGEAELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 320

  Fly   223 WFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGAL 287
            |...::|:.....::.:|.||||.|||.|.|.:.::.:.|...|:.|..|........||.....
Human   321 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVA 385

  Fly   288 AARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIP 352
            |..:.|::.:.:||||||.:|..::.....|..|...|||.:..||.||.|::.:..:...|.:|
Human   386 AGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELP 450

  Fly   353 GTCLCALMTKYLGRKKT---LLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVY 414
            ...|..|..:|.||:.|   .||.... |.|..||  :|:..::.....|.:|...:...|...|
Human   451 SKLLVYLSVRYAGRRLTQAGTLLGTAL-AFGTRLL--VSSDMKSWSTVLAVMGKAFSEAAFTTAY 512

  Fly   415 LYGGELFPTVVRSSGVGLCSMVGRIGSIVAPL--IVDLAAYGLWVA--PLIFGIFSILAMLGTIF 475
            |:..||:|||:|.:|:||.::|||:|..:|||  ::|    |:|::  .|.:|..::||....:.
Human   513 LFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLD----GVWLSLPKLTYGGIALLAAGTALL 573

  Fly   476 LPETRGTPLPETLEDGE 492
            |||||...||||::|.|
Human   574 LPETRQAQLPETIQDVE 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	135/477 (28%)
		MFS	87..477	CDD:119392	127/465 (27%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	156/588 (27%)
		MFS	206..563	CDD:119392	112/368 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.940