Protein Alignment CG8654 and Slc22a7

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_659105.2
• Gene: Slc22a7 / 108114
• MGIID: 1859559
• Length: 540
• Species: Mus musculus
• Alignment Length: 531
• Identity: 154/531 - (29%)
• Similarity: 245/531 - (46%)
• Gaps: 58/531 - (10%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLA-----------APTPLS-----CKTE 70
            :.::.::|.|..:||....::.|.:|....|.|..||:|           ||..||     .||.
Mouse     4 EELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHHCALPDAPANLSHQDLWLKTH 68

  Fly    71 ----------------------NVT-------------DPCSDECSE-TEFDTSVFQSTIITEWN 99
                                  |||             :|.:..||: .|:|.|.|.|||.|||:
Mouse    69 LPRETDGSFSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWD 133

  Fly   100 LTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCL 164
            |.|:.:.|..::.:...:|:|.|::::|..:||:|||...|......|..||:...|..|..:..
Mouse   134 LVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVT 198

  Fly   165 FRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSIT 229
            .|.|...|.||.......|.:|.:..:.|.:..::....:..|...|.|..|.||.|||...:.|
Mouse   199 TRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAAT 263

  Fly   230 IFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVK 294
            :..:..:|.||.||||.|||.|.|:::::.|.|...||.|..|........||....:...:..:
Mouse   264 LPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEALNKVITMERVSQ 328

  Fly   295 KGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCAL 359
            :.:.:|||||..:|..::.....|..|...|||.....|.||..::.:..:...|.:|.......
Mouse   329 RPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFF 393

  Fly   360 MTKYLGRKKT---LLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELF 421
            :.:.:||:.|   :||:...: .|:.||  :|:..::.......||...:...|...||:..||:
Mouse   394 LVRLVGRRLTEAGMLLATALT-FGISLL--VSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELY 455

  Fly   422 PTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPE 486
            |||:|.:|:|..:::||:|:.:|||:|.|....|.:..|.:|..|.||....:.||||:...|||
Mouse   456 PTVLRQTGMGFTALIGRLGASLAPLVVLLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPE 520

  Fly   487 TLEDGETFGRK 497
            |::|.|..|||
Mouse   521 TIQDVERKGRK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	118/398 (30%)
Slc22a7	NP_659105.2	2A0119	11..521	CDD:273328	147/512 (29%)