Protein Alignment CG8654 and slc22a8

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_002937554.2
• Gene: slc22a8 / 100490266
• XenbaseID: XB-GENE-22061134
• Length: 556
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 162/523 - (30%)
• Similarity: 248/523 - (47%)
• Gaps: 57/523 - (10%)

  Fly    24 IISQIGDFRRYQ-----LFFFFIVLL-----------------CKFG-TGWHT-----LGHIFLA 60
            ::.:.|...|:|     |..|.|:|:                 ||.. ||:.:     .|:..|:
 Frog     6 LLERTGGMGRFQITQVVLLCFPILLMASHNLLQNFSAAIPDHKCKANDTGYQSNSTDETGYERLS 70

  Fly    61 AP-----TPLSC-------------------KTENVTDPCSDECSETEFDTSVFQSTIITEWNLT 101
            ||     .|..|                   .:|..|.||:   ...|:....|.|||||||:|.
 Frog    71 APLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCT---IGWEYSKDEFSSTIITEWDLV 132

  Fly   102 CESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFR 166
            |..|....|:|||.|.|:|.|:|:.|..:||||||...:...|...::|:....||.|..||:||
 Frog   133 CGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFR 197

  Fly   167 FLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIF 231
            ||..:|.:|....:..|::|.|..:.|.:...|....:..|...||..||.:|:|||.|..:::.
 Frog   198 FLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLP 262

  Fly   232 SIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKG 296
            ..::.:|.|..|||.|||..:||.:|::|.:.|:|..|....|..:..:|:....:.......|.
 Frog   263 FFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKITLESLKSEMIKELASAKS 327

  Fly   297 --TVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCAL 359
              :|:||.||..:|..:..::..|......|||.|..:.....:|::...|...|..|...:.|.
 Frog   328 SYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSAT 392

  Fly   360 MTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTV 424
            ...|:|||.|..:|.....:.:|....:..:.:.||.:.|..|....:.:|..::||..||:|||
 Frog   393 AMIYVGRKFTQFMSLILGGIAIIANIFVPNELQTVRTSLAVFGKGCLAASFSCIFLYTTELYPTV 457

  Fly   425 VRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLE 489
            :|.||:|:||.:.|||.|||||:..|.....:|..||:|...|::.|...|||||...|||:|:|
 Frog   458 IRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFFLPETVNKPLPDTIE 522

  Fly   490 DGE 492
            :.|
 Frog   523 EVE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	131/396 (33%)
slc22a8	XP_002937554.2	MFS_SLC22A6_OAT1_like	105..510	CDD:341004	134/407 (33%)