Protein Alignment CG8654 and slc22a20

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_004913725.1
• Gene: slc22a20 / 100489586
• XenbaseID: XB-GENE-6463910
• Length: 572
• Species: Xenopus tropicalis
• Alignment Length: 532
• Identity: 161/532 - (30%)
• Similarity: 258/532 - (48%)
• Gaps: 69/532 - (12%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA--------PT----------------- 63
            ::..:|...|:|:....::|:.....|.|.....|.||        |:
 Frog     6 LLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYDQDHLPAFI 70

  Fly    64 -------PLSC--------------KTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQL 107
                   ||||              .:.|.|:||.|   ...:|.|.|.|||:|||:|.|:.:::
 Frog    71 PMDESEKPLSCLRYRKALHSMWTNGTSTNHTEPCED---GWVYDKSDFSSTIVTEWDLVCKLRKM 132

  Fly   108 ASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVA 172
            ..::|||.|.|:|.|::|.|..:||.|||...:....:..:.|......|.:..||.||.|..:|
 Frog   133 RQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFITYCTFRCLCGIA 197

  Fly   173 TAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVI 237
            .:|....:..|::|...||.|.::..|:...|..|...||..||.||||||.||:::.....|.:
 Frog   198 FSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTCGQILLAALAYGIREWRWLQFAVSAPFYFFFL 262

  Fly   238 YIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAPTETIRPEIEAAYGALAARQPVKKGTVVD 300
            |.||||||.|||...|:..:::|.|:::|..|  :...:.:...|..::......|..:..::.|
 Frog   263 YSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEMILISHMQSELNQVKRPHSLFD 327

  Fly   301 LFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLG 365
            |||||.||..||.:...|....:.:||....:...|.:||:.......:.:|...:.||:..|:|
 Frog   328 LFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFGAIDMPAKVVAALLMTYMG 392

  Fly   366 RKKT----LLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVR 426
            |:.|    |:|    |.:.|:..|.:....:.:|:..|..|....:.:|...||:.|||||||:|
 Frog   393 RRVTQATVLIL----SGVALLTNAFIPQGMKILRMVLAVFGKGCMAASFACAYLFSGELFPTVIR 453

  Fly   427 SSGVGLCSMVGRIGSIVAPLIVDLAAYGLW-VAPL----IFGIFSILAMLGTIFLPETRGTPLPE 486
            .:|:|:.:|:.|:||:||||::     .|| ::|:    |:||.:|:|.....||.||....|||
 Frog   454 QTGMGVVAMMARVGSVVAPLVL-----LLWEISPILPSAIYGIAAIIAGGAATFLMETNNQQLPE 513

  Fly   487 TLEDGETFGRKK 498
            ::|:.|...:.|
 Frog   514 SVEEVEARSQGK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	133/405 (33%)
slc22a20	XP_004913725.1	MFS	101..485	CDD:475125	131/395 (33%)