DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	161/532 - (30%)
Similarity:	258/532 - (48%)	Gaps:	69/532 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA--------PT----------------- 63
            ::..:|...|:|:....::|:.....|.|.....|.||        |:
Frog     6 LLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYDQDHLPAFI 70

  Fly    64 -------PLSC--------------KTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQL 107
                   ||||              .:.|.|:||.|   ...:|.|.|.|||:|||:|.|:.:::
Frog    71 PMDESEKPLSCLRYRKALHSMWTNGTSTNHTEPCED---GWVYDKSDFSSTIVTEWDLVCKLRKM 132

  Fly   108 ASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVA 172
            ..::|||.|.|:|.|::|.|..:||.|||...:....:..:.|......|.:..||.||.|..:|
Frog   133 RQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFITYCTFRCLCGIA 197

  Fly   173 TAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVI 237
            .:|....:..|::|...||.|.::..|:...|..|...||..||.||||||.||:::.....|.:
Frog   198 FSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTCGQILLAALAYGIREWRWLQFAVSAPFYFFFL 262

  Fly   238 YIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAPTETIRPEIEAAYGALAARQPVKKGTVVD 300
            |.||||||.|||...|:..:::|.|:::|..|  :...:.:...|..::......|..:..::.|
Frog   263 YSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEMILISHMQSELNQVKRPHSLFD 327

  Fly   301 LFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLG 365
            |||||.||..||.:...|....:.:||....:...|.:||:.......:.:|...:.||:..|:|
Frog   328 LFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFGAIDMPAKVVAALLMTYMG 392

  Fly   366 RKKT----LLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVR 426
            |:.|    |:|    |.:.|:..|.:....:.:|:..|..|....:.:|...||:.|||||||:|
Frog   393 RRVTQATVLIL----SGVALLTNAFIPQGMKILRMVLAVFGKGCMAASFACAYLFSGELFPTVIR 453

  Fly   427 SSGVGLCSMVGRIGSIVAPLIVDLAAYGLW-VAPL----IFGIFSILAMLGTIFLPETRGTPLPE 486
            .:|:|:.:|:.|:||:||||::     .|| ::|:    |:||.:|:|.....||.||....|||
Frog   454 QTGMGVVAMMARVGSVVAPLVL-----LLWEISPILPSAIYGIAAIIAGGAATFLMETNNQQLPE 513

  Fly   487 TLEDGETFGRKK 498
            ::|:.|...:.|
Frog   514 SVEEVEARSQGK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	138/412 (33%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	132/400 (33%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	131/395 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010