DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and slc22a16

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_002936981.2	Gene:	slc22a16 / 100488673	XenbaseID:	XB-GENE-961385	Length:	567	Species:	Xenopus tropicalis

Alignment Length:	548	Identity:	149/548 - (27%)
Similarity:	245/548 - (44%)	Gaps:	84/548 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCKT-ENVT-------------- 73
            :...:|.|.|:|...:|.........|.|.|..:|:|......|:. ||::
Frog     4 LFDYVGHFGRFQALIYFSSAFQAISCGIHYLASVFIAITPKFICRAPENISSVLLPNASTLRLED 68

  Fly    74 -----------------------DPCSD--------------------ECSE-TEFDTSVFQSTI 94
                                   :.||.                    .||. ..:|.:..:|:|
Frog    69 VWELWTPKDYLVVKQENGDIWELNQCSRFKRENTSYLTYSYDGNKTLFSCSNGYYYDNTNLESSI 133

  Fly    95 ITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYY 159
            :|:|:|.||.:.||.|.|...|.|:|.|:::||..|||.|||.........|.:.|:.|..:..|
Frog   134 VTDWHLVCEREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRRLILWLTSTGQFLFGIAVAFTFDY 198

  Fly   160 WFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWF 224
            :.:.:.|||:|:.::|.....||.:.|.||.|.|...::.....|.:|...::|..:.:|.|..:
Frog   199 YSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARSWASMHVHAFFAVGVMIVSLVGFLVRTWWMY 263

  Fly   225 QFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPT-----------ETIRP 278
            |..:::.::.||:..|::||:|.||::.||..:..|::..|.|.||..|           ||.:.
Frog   264 QIILSLTTLPFVLCCWMLPETPFWLYSQGKHKEVEKLIGTIEKWNKISTPCKLSELCSVQETQKT 328

  Fly   279 EIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISN 343
            |::.          :||.:|:|||.......:|:.:...|....:.||..|.....||||.:::.
Frog   329 EMDT----------LKKHSVLDLFYNWSFARRTVTVWLIWFTGSLGYYVFALNSVNLGGNEYLNL 383

  Fly   344 AIAAGVGIPGTCLCALMTKYLGRKKTL--LLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGA 406
            .:.:.|.||...:.......:||:.||  .|.......|:|:|  :......|.:..:..|.|..
Frog   384 FLTSAVEIPSYIVACFGMDKIGRRNTLAPFLILSAVICGIIML--IPQDHSTVTIAMSMGGKFSI 446

  Fly   407 SITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAML 471
            ::.|..:|||..||:||:|||..||..||:.||||:|||..|.|....:::..::.||.:.|..:
Frog   447 AVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYLTDVWIFMPQMLVGIMAFLTGV 511

  Fly   472 GTIFLPETRGTPLPETLEDGETFGRKKK 499
            .|:.||||.|.||..|:|:....|...:
Frog   512 LTLKLPETLGVPLTSTIEEAAEMGTNNR 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	129/414 (31%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	121/402 (30%)
slc22a16	XP_002936981.2	MFS_SLC22A16_CT2	111..517	CDD:340933	124/417 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010