Protein Alignment CG8654 and slc22a6

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_002937540.1
• Gene: slc22a6 / 100487511
• XenbaseID: XB-GENE-5842250
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 532
• Identity: 160/532 - (30%)
• Similarity: 256/532 - (48%)
• Gaps: 61/532 - (11%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCK-------------------- 68
            |:..||...|||:....::.|..|....|.|...|.||.....|:
 Frog     6 ILESIGGMGRYQVIHVVLLSLPVFMLASHNLMQNFTAAIPRHRCQINGSFEETNFTGPWLRALVP 70

  Fly    69 -------------------------TENVTDPCSDECSE-TEFDTSVFQSTIITEWNLTCESKQL 107
                                     |:||.:..::.|.: ..:|.|.|.|||||:|:|.|..:::
 Frog    71 MKPTGEFSKCLRYTTPQYHLLMDNFTQNVDELETETCVDGWVYDHSEFASTIITQWDLVCNHRRM 135

  Fly   108 ASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVA 172
            ..::|||.|.|:|.||::||..:|::||||..:.......:||:....||.|.:||:||||...|
 Frog   136 RQVAQSIYMAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAFSPNYIWYCIFRFLTGTA 200

  Fly   173 TAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVI 237
            .:|.:..|:.|::|.:....|...:......:.:|...|...|:.||:|.|.|.:.::....:.:
 Frog   201 LSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWLQLAASLPFFFYFL 265

  Fly   238 YIWLVPESPRWLFTTGKLDKSIKILEKIAKCN-------KAPTETIRPEIEAAYGALAARQPVKK 295
            |.|.:|||.|||..:||.:.:.|.|:|:||.|       |...|.::..::....|      .|.
 Frog   266 YSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQREISA------SKH 324

  Fly   296 GT--VVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCA 358
            .|  |:||.|||.:|..:..::..|......|||.|..:.:.|.:|:|...|...|.||......
 Frog   325 STYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKFFSY 389

  Fly   359 LMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPT 423
            .:..|:||:....|:...:.:.:::..|:....:.||.:.|..|....:.:|..::||.|||:||
 Frog   390 FVMTYIGRRVLQALTLILAGIAILVNICVPQDYQTVRTSMAVFGKGCLAASFNCLFLYTGELYPT 454

  Fly   424 VVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETL 488
            |:|.||:||.:|:.|:|.|:|||..........:..:|||...||:.:...|||||.|.|||||:
 Frog   455 VIRQSGMGLGTMMARLGGIIAPLAQMTGDIYHSLPLIIFGCLPILSGIAGCFLPETLGVPLPETI 519

  Fly   489 EDGETFGRKKKD 500
            ||.|:..:|:|:
 Frog   520 EDVESSDKKQKN 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	135/410 (33%)
		MFS	87..477	CDD:119392	126/398 (32%)
slc22a6	XP_002937540.1	MFS_SLC22A6_OAT1_like	102..508	CDD:341004	128/411 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.140