Protein Alignment CG8654 and sv2a

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 115/563 - (20%)
• Similarity: 178/563 - (31%)
• Gaps: 199/563 - (35%)

  Fly   102 CESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFR 166
            |.|.....:...||.||::.|:.|:|..|||.|||...|....:..:..........|..:...|
 Frog   185 CLSDSNKGMLGLIVYLGMMVGAFLWGGMADRIGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCR 249

  Fly   167 FLVAVATAGTMTTSFVLLMEIVGPKKRE----------MVAILYQ-------IP-----FNIGHA 209
            .|..|...|::...|....|.:..:||.          |:..:|.       ||     |.:|.
 Frog   250 LLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFQMGS- 313

  Fly   210 SLALFAYFIREWRWFQFSITIFSIVFVI-YIWLVPESPRWLFTTGKLDKSIKILEKIAKCNK--- 270
                 ||....||.|.. :..|..||.| .:..:|||||:....||.|::..:|:::...|.
 Frog   314 -----AYQFHSWRVFVL-VCAFPSVFAIGALTTMPESPRFFLENGKHDEAWMVLKQVHDTNMRAK 372

  Fly   271 ---------APTETIRP-----EIEAAYGALAARQPVKKGTVVDL-----------FRTPYMRIK 310
                     ...:||:.     ||::..|||..|..:|   :::|           |...|.||
 Frog   373 GHPERVFSVTQIKTIKQDDELVEIQSDTGALHRRWMIK---LLNLSQEVWANFHQCFAPEYRRI- 433

  Fly   311 TIFMANNWLVVCMVYYG-------------TAQYVS----------------------------- 333
            |:.|...|..:...|||             ...|.|
 Frog   434 TLMMMAVWFTMSFSYYGLTVWFPDMIKHLQNIDYASRTKYFHNESVNNFNFNFTLENQVHRKGEY 498

  Fly   334 ---------------------------ALGGNIFISNA--------------------------- 344
                                       ....|.|..|.
 Frog   499 HNDKFIGLKLKSVIFEDSLFTDCYFEDITSSNTFFKNCSFIRTMFYNTDLFDYKFINSKFTNSTF 563

  Fly   345 ----------------------IAAGVG----IPGTCLCALMTKYLGRKKTLLLSNGCSALGLIL 383
                                  ..:.:|    :||..:.||:...:||.:.|..|:..|.:....
 Frog   564 LHSKEGCQLDFSDDINNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVMSCISCFF 628

  Fly   384 LACLSTQAEAVRVTCATIGLF-GASITFPNVY-LYGGELFPTVVRSSGVG----LCSMVGRIGSI 442
            |...::::..:.:.|    || |.||...|.. :...||:|:..|::..|    ||.:...:|..
 Frog   629 LFFGNSESAMIALLC----LFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGIS 689

  Fly   443 VAPLIVDLA-AYGLWVAPLIFGIFSILAMLGTIFLPETRGTPL 484
            :....|.:| |..:.:|.....:.|.||:.    ||||||..|
 Frog   690 IFTSFVGVAKAVPILLASAALAVGSFLALK----LPETRGQVL 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	108/554 (19%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	115/563 (20%)