Protein Alignment CG8654 and sv2bb

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_005161575.1
• Gene: sv2bb / 100006427
• ZFINID: ZDB-GENE-030131-2789
• Length: 687
• Species: Danio rerio
• Alignment Length: 629
• Identity: 122/629 - (19%)
• Similarity: 205/629 - (32%)
• Gaps: 240/629 - (38%)

  Fly    62 PTPLSCKTENVTDPCSD---ECSETEFDTSVFQSTIITEWNLTCESKQ-------LASLSQS--- 113
            ||....:.|.:.:...|   :|...:|..::|   ::....|..:|.:       |.|..:.
Zfish    84 PTDTVSELEELAEQYEDIMEDCGHGKFQWTLF---VVLGLALMADSVECFVVALVLPSAEKDMCL 145

  Fly   114 ----------IVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFL 168
                      ||.||::||:.::|..||:.|||...:....|..|:......:..|.|:..||..
Zfish   146 SHAEKGMLGLIVFLGMMFGAFIWGGLADKVGRRKCLIIVLAMNCISAFFSSFAQGYGFFLFFRLF 210

  Fly   169 VAVATAGTMTTSFVLLMEIVGPKKRE----------MVAILYQ-------IP-----FNIGHASL 211
            ..:...|::...:....|.:...||.          |:..:|.       ||     |::|
Zfish   211 SGIGIGGSVPIVYSYFSEFLQMDKRGEHLSWLCMFWMMGGIYASFTAWGIIPRYGWGFSMG---- 271

  Fly   212 ALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN------- 269
              ..:....||.|.....:.:|...:.:..:|||||:|....|.|::..||:::...|
Zfish   272 --TEFQFHSWRVFVLVCALPAIAAFVGLMFMPESPRFLLENAKHDEAWMILKQVHDTNWRAKGQP 334

  Fly   270 -KAPTET-IRP---------EIEAAYGALAARQPVKKGT--------VVDLFRTPYMRIKTIFMA 315
             |..|.| ||.         ||:.|.|....|..|:..|        |:.||... :|:.|:.||
Zfish   335 EKVFTVTQIRTPKTQEDEFIEIQTATGTAFQRWVVRTLTLTKLVIKNVLSLFGRE-LRLATLLMA 398

  Fly   316 NNWLVVCMVYYGTA--------------------------------------------QYVSALG 336
            ..|..:...|||.:                                            :|::...
Zfish   399 IIWFTMAFSYYGLSVWFPDMIKHLQHEEYESKVKVFHREKVEQFHFNFSLENQVHKEGEYINDKF 463

  Fly   337 GNI--------------------------------------------------------FISNA- 344
            .||                                                        |:.|.
Zfish   464 INIEMKSVKFEDSLFVDCFFENVRSTETMFENCTIRSTVFYDTDLYEEKFIDCTMENVTFLHNKK 528

  Fly   345 ---------------IAAGVG----IPGTCLCALMTKYLGRKK----TLLLSNGCSALGLILLAC 386
                           :.:.:|    :||..:.||....:||.|    ::|:|.||:    ..|..
Zfish   529 GCHLDYEEDNDVLIYLVSFLGSLAVLPGNIISALFMDKIGRIKIIGGSMLVSAGCT----FFLFL 589

  Fly   387 LSTQAEAVRVTCATIGLFGASITFPN-VYLYGGELFPTVVRSSGVG----LCSMVGRIGSI---- 442
            ..:||..:...|.   .:|.|:...| :.:...||:|...|::..|    :|.:...:||.
Zfish   590 SFSQAAIIAWQCL---FYGVSVAAWNGIQVITVELYPASKRATAFGFLNAMCKLAAILGSSIFAS 651

  Fly   443 ------VAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETR 480
                  |.|:::..||       |:.|  .:||:.    |||||
Zfish   652 FIGITKVIPILLSFAA-------LVSG--GVLALK----LPETR 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	112/601 (19%)
sv2bb	XP_005161575.1	synapt_SV2	38..687	CDD:130366	122/629 (19%)