Protein Alignment CG8654 and slc22a5

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_021324939.1
• Gene: slc22a5 / 100000685
• ZFINID: ZDB-GENE-091012-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 532
• Identity: 143/532 - (26%)
• Similarity: 239/532 - (44%)
• Gaps: 86/532 - (16%)

  Fly    39 FFIVLLC-----KFGTGWHTLGHIFLAAPTPLSCKTE---------------------------- 70
            |||.|.|     ...||.|.|..:|:||.....|:.:
Zfish    17 FFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRVDVNLTEDWLEASAPTETLSNGDLQVSQCW 81

  Fly    71 --------------------NVTDPCSDECSE-TEFDTSVFQSTIITEWNLTCESKQLASLSQSI 114
                                |:||...:.|.: ..:...|:.|||::||:|.|:|:....|:.|.
Zfish    82 RYSLQTLTNLSGQGYSPGQINITDIPRERCEDGWVYSADVYHSTIVSEWDLVCDSEWRVPLASST 146

  Fly   115 VMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTT 179
            :.:|.|.|||:.|..:||:||:.........:.:.......||.:..:|:..|.:.........|
Zfish   147 LYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSPSWLIFCVLYFFIGAFQISLYIT 211

  Fly   180 SFVLLMEIVGPKKREMVAILYQ-IPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVP 243
            :|||..|::....|.:...|.. :.:.:|:..|...|:.||.||.....::..::|::...||:|
Zfish   212 AFVLGNEVLSGSLRVLFTTLGAFLHYCVGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIP 276

  Fly   244 ESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEI--------EAAYGALAARQPVKKGTVVD 300
            ||||||.:.|.:.:|..||...|:.|:.|.    ||:        |||:       ...|.:.:|
Zfish   277 ESPRWLLSQGHVQESEAILRDAARKNRVPA----PEVIFKQSQIKEAAF-------QKSKYSALD 330

  Fly   301 LFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLG 365
            :.||..:|..|......|:.:.:.|:|.:...:.|.|:.|::..::|...:|...:...:.|...
Zfish   331 VLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNCFLSAVTEVPAYIVSTFLLKSCP 395

  Fly   366 RKKT----LLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVR 426
            |:..    |::..|.    |:|:..:..:.:.:.:.....|.||.:::|..||:|..||:|||:|
Zfish   396 RRPVLSAFLVIGGGF----LLLVQLIPDRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLR 456

  Fly   427 SSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTPLPETLED- 490
            :.|:|:||...|||||.||.|:.|..:...:..::.|..:|.|.|..:|||||.|..|||.||.
Zfish   457 NLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQM 521

  Fly   491 --GETF-GRKKK 499
              ..:| ||.|:
Zfish   522 QKSRSFPGRDKQ 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	112/408 (27%)
slc22a5	XP_021324939.1	MFS_SLC22A4_5_OCTN1_2	104..507	CDD:340934	115/417 (28%)