DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Toll-7 and RLP38

DIOPT Version :9

Sequence 1:NP_523797.1 Gene:Toll-7 / 37272 FlyBaseID:FBgn0034476 Length:1446 Species:Drosophila melanogaster
Sequence 2:NP_188953.1 Gene:RLP38 / 821887 AraportID:AT3G23120 Length:784 Species:Arabidopsis thaliana


Alignment Length:843 Identity:191/843 - (22%)
Similarity:305/843 - (36%) Gaps:269/843 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 DYSSLLSNVPAASPVPANPSQPSGPANQ----CSWSYNGTSSVHCALRLIERQPGLDLQGADGSS 109
            |....|..:....|:|:...|  .|.|:    |||     ..|.|...|.|              
plant    41 DQRDALLELQKEFPIPSVILQ--NPWNKGIDCCSW-----GGVTCDAILGE-------------- 84

  Fly   110 QLTIQCSELYLFESTLPV------AVFARLQTLEALRLDSCKLL-QLPNNAFEGLATLKSLRLST 167
               :...:|| |.||...      |:| :||.|..|.|.:|.|. ::| ::.|.|:.|..|.|||
plant    85 ---VISLKLY-FLSTASTSLKSSSALF-KLQHLTHLDLSNCNLQGEIP-SSIENLSHLTHLDLST 143

  Fly   168 HNSEWGPTRTLELFPDSLGGLKQLTDLDLGDNNLR-QLPSGF----------------------L 209
            ::       .:...|.|:|.|.||..:||..|:|| .:|:.|                      |
plant   144 NH-------LVGEVPASIGNLNQLEYIDLRGNHLRGNIPTSFANLTKLSLLDLHENNFTGGDIVL 201

  Fly   210 CPVGNLQVLNLTRNRIRT-----------AEQMGFADMN-------------------------- 237
            ..:.:|.:|:|:.|..::           .||: |.:.|                          
plant   202 SNLTSLAILDLSSNHFKSFFSADLSGLHNLEQI-FGNENSFVGLFPASLLKISSLDKIQLSQNQF 265

  Fly   238 ---CGAGSGSAGSELQVLDASHNELRSISESWGISRLRRLQHLNLAYNNLSELSGEALAGLASLR 299
               ...|:.|:.|.|.:||.|||.......| .:|:|..|:.|:|::||...||..:::.|.:|.
plant   266 EGPIDFGNTSSSSRLTMLDISHNNFIGRVPS-SLSKLVNLELLDLSHNNFRGLSPRSISKLVNLT 329

  Fly   300 IVNLSNNHLE-TLPEGLFAGSKELREIHLQQNELYELPKGLFHRLEQLLVVDLSGNQLTSNHVD- 362
            .:::|.|.|| .:|..::..| .|:.:.|..|..::|.|.    :|.:....|.|..|.||.:. 
plant   330 SLDISYNKLEGQVPYFIWKPS-NLQSVDLSHNSFFDLGKS----VEVVNGAKLVGLNLGSNSLQG 389

  Fly   363 -------NTTFAGLIRLIVLNLAHNALTRIDYRTFKELYFLQILNLRNNSIGHIEDNAFLPLYNL 420
                   |..|     :..|:|:.|..|....:..|.......|||||||:     :.|||    
plant   390 PIPQWICNFRF-----VFFLDLSDNRFTGSIPQCLKNSTDFNTLNLRNNSL-----SGFLP---- 440

  Fly   421 HTLNLAENRLHTLDDKLFNGLYVLSKLTLNNNLISVVEPAVFKNCSDLKELDLSSNQLNEV-PRA 484
             .|.:....|.:||             ...||.:..: |....||.|::.|::..|::.:. |..
plant   441 -ELCMDSTMLRSLD-------------VSYNNFVGKL-PKSLMNCQDMEFLNVRGNKIKDTFPFW 490

  Fly   485 LQDLAMLRTLDLGENQI--RTFDNQSFKNLHQLTGLRLIDNQ-IGNITVGMFQDLPRLSV----- 541
            |.....|..|.|..|..  ..:::.::....:|:.:.:.:|. :|::....|.:...::.     
plant   491 LGSRKSLMVLVLRSNAFYGPVYNSTTYLGFPRLSIIDISNNDFVGSLPQDYFANWTEMATVWDIN 555

  Fly   542 -LNLAKNR---------IQSIERGSF-DKNFELEAIRLD---RNFLADINGVFATLVSLLWLNLS 592
             ||.|:|.         :|:|:|.:: ..||.:.|..:|   :....|.|.:|...         
plant   556 RLNYARNTSSRTIQYGGLQTIQRSNYVGDNFNMHADSMDLAYKGVDTDFNRIFRGF--------- 611

  Fly   593 ENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVKTLDASHNRITEIGPMSIPNTIEL 657
                                                     |.:|.|.||.:...|.||....||
plant   612 -----------------------------------------KVIDFSGNRFSGHIPRSIGLLSEL 635

  Fly   658 LFIN---NNLIGNVQPNAFVDKANLARVDLYANQLSKLQLQQLRVAPVVAPKPLPEFYLGGNPFE 719
            |.:|   |...||:.| :..:..||..:||..|.||.           ..|:.|      ||   
plant   636 LHLNLSGNAFTGNIPP-SLANITNLETLDLSRNNLSG-----------EIPRSL------GN--- 679

  Fly   720 CDCTMDWLQRINNLTTRQH-----PRVMDMANIECVMPHARGAAVRPLSGLRPQDFLCRYESH 777
                :.:|..||  .:..|     ||........|       ::.....||...|.:|| |||
plant   680 ----LSFLSNIN--FSHNHLQGFVPRSTQFGTQNC-------SSFVGNPGLYGLDEICR-ESH 728

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-7NP_523797.1 LRR_8 135..201 CDD:290566 22/66 (33%)
leucine-rich repeat 136..159 CDD:275380 8/23 (35%)
leucine-rich repeat 160..190 CDD:275380 9/29 (31%)
LRR_8 189..259 CDD:290566 27/132 (20%)
leucine-rich repeat 191..214 CDD:275380 9/45 (20%)
leucine-rich repeat 215..248 CDD:275380 10/72 (14%)
LRR_RI 247..501 CDD:238064 71/263 (27%)
LRR_8 247..308 CDD:290566 21/60 (35%)
leucine-rich repeat 249..273 CDD:275380 9/23 (39%)
leucine-rich repeat 274..297 CDD:275380 8/22 (36%)
LRR_8 297..356 CDD:290566 15/59 (25%)
leucine-rich repeat 298..321 CDD:275380 7/23 (30%)
leucine-rich repeat 322..345 CDD:275380 5/22 (23%)
LRR_8 345..406 CDD:290566 18/68 (26%)
leucine-rich repeat 346..371 CDD:275380 7/32 (22%)
leucine-rich repeat 372..395 CDD:275380 5/22 (23%)
leucine-rich repeat 396..419 CDD:275380 10/22 (45%)
LRR_8 419..478 CDD:290566 12/58 (21%)
leucine-rich repeat 420..443 CDD:275380 4/22 (18%)
leucine-rich repeat 444..467 CDD:275380 5/22 (23%)
LRR_RI 466..622 CDD:238064 27/178 (15%)
leucine-rich repeat 468..488 CDD:275380 4/20 (20%)
LRR_8 491..549 CDD:290566 12/75 (16%)
leucine-rich repeat 491..514 CDD:275380 4/24 (17%)
leucine-rich repeat 515..536 CDD:275380 4/21 (19%)
leucine-rich repeat 539..562 CDD:275380 8/38 (21%)
leucine-rich repeat 563..585 CDD:275380 5/24 (21%)
leucine-rich repeat 586..626 CDD:275380 0/39 (0%)
leucine-rich repeat 627..653 CDD:275380 8/25 (32%)
LRRCT 716..772 CDD:214507 11/60 (18%)
LRRNT 796..830 CDD:214470
leucine-rich repeat 812..829 CDD:275380
leucine-rich repeat 833..854 CDD:275380
LRR_8 853..913 CDD:290566
leucine-rich repeat 855..878 CDD:275380
LRR_4 878..918 CDD:289563
leucine-rich repeat 879..902 CDD:275380
leucine-rich repeat 903..926 CDD:275380
leucine-rich repeat 927..953 CDD:275380
TIR 1098..1235 CDD:214587
RLP38NP_188953.1 PLN00113 11..>721 CDD:331614 185/833 (22%)
leucine-rich repeat 112..135 CDD:275380 8/23 (35%)
leucine-rich repeat 136..159 CDD:275380 9/29 (31%)
leucine-rich repeat 160..183 CDD:275380 8/22 (36%)
leucine-rich repeat 184..206 CDD:275380 1/21 (5%)
leucine-rich repeat 207..254 CDD:275380 8/47 (17%)
leucine-rich repeat 255..276 CDD:275380 1/20 (5%)
leucine-rich repeat 280..303 CDD:275380 9/23 (39%)
leucine-rich repeat 304..327 CDD:275380 8/22 (36%)
leucine-rich repeat 352..376 CDD:275380 6/27 (22%)
leucine-rich repeat 377..397 CDD:275380 5/19 (26%)
leucine-rich repeat 401..424 CDD:275380 5/22 (23%)
leucine-rich repeat 425..448 CDD:275380 11/32 (34%)
leucine-rich repeat 449..472 CDD:275380 8/36 (22%)
leucine-rich repeat 473..496 CDD:275380 4/22 (18%)
leucine-rich repeat 523..545 CDD:275380 4/21 (19%)
leucine-rich repeat 659..682 CDD:275380 10/46 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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