DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Toll-7 and RLP28

DIOPT Version :9

Sequence 1:NP_523797.1 Gene:Toll-7 / 37272 FlyBaseID:FBgn0034476 Length:1446 Species:Drosophila melanogaster
Sequence 2:NP_180867.1 Gene:RLP28 / 817870 AraportID:AT2G33080 Length:740 Species:Arabidopsis thaliana


Alignment Length:687 Identity:160/687 - (23%)
Similarity:256/687 - (37%) Gaps:179/687 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 LRLDSCKLLQL-PNNAFEGLATLKSLRLSTHNSEWGPTRTLELFPDSLGGLKQLTDLDLGDNNLR 202
            |:|::|....| ||::......|:.|.||.:|.      |...||...|.|.::..|||..|:..
plant    80 LQLNACLSGTLNPNSSLFWFHQLRFLNLSHNNF------TSTSFPSEFGNLNKVEVLDLSFNSFT 138

  Fly   203 -QLPSGFLCPVGNLQVLNLTRNRIRTAEQMGFADMNCGAGSGSAGSELQVLDASHNELRSISESW 266
             |:||.|    .||                               |:|..|..|:|:|     :.
plant   139 GQVPSSF----SNL-------------------------------SQLTELHLSNNQL-----TG 163

  Fly   267 G---ISRLRRLQHLNLAYNNLSELSGEALAGLASLRIVNLSNNH------------LETLPEGLF 316
            |   :..|..|.||:...|..|.....:|..:..|..:||..||            ||.|..||.
plant   164 GFPQVQNLTNLSHLDFENNKFSGTVPSSLLMMPFLSYLNLYGNHFTGSIEVSTSSKLEILYLGLK 228

  Fly   317 AGSKELRE-----IHLQQNEL------YELPKGLFHRLEQLLVVDLSGNQLTSNHVDNTTFAGLI 370
            ....::.|     |:|::.||      |.|...||..|:.|..:|||||.::...:.:..:   |
plant   229 PFEGQILEPISKLINLKRLELSFLNISYPLDLNLFSSLKSLTYLDLSGNSISPRSLRSDLY---I 290

  Fly   371 RLIVLNLAHNALTRIDY-RTFKELYFLQILNLRNNSIGHIEDNAFLP-----LYNLHTLNLAENR 429
            .|.:..|.......|:: ...|.|..|:.:::.||.|     |..:|     |..|.:::||.|.
plant   291 PLTLEKLLLEQCGIIEFPNILKTLQKLEYIDMSNNRI-----NGKIPEWLWRLPRLRSMSLANNS 350

  Fly   430 LHTLD---DKLFNGLYVLSKLTLNN-------------------NLISVVEPAVFKNCSDLKELD 472
            .:..:   |.|.|....:..:..||                   |..|...|....|.|.|..|.
plant   351 FNGFEGSTDVLVNSSMEILFMHSNNIQGALPNLPLSIKAFSAGYNNFSGEIPLSICNRSSLAALS 415

  Fly   473 LSSNQL-NEVPRALQDLAM---------------------LRTLDLGENQIRTFDNQSFKNLHQL 515
            |..|.. .::|:.|.:|..                     |:|||:|.|.|.....:|..|...|
plant   416 LPYNNFTGKIPQCLSNLTFVHLRKNNLEGSIPDTLCAGDSLQTLDIGFNLISGTLPRSLLNCSSL 480

  Fly   516 TGLRLIDNQIGNITVGMFQDLPRLSVLNLAKNRIQSIERGSFDKNFELEAIRLDRNFLAD--ING 578
            ..|.:.:|:|.:......:.||.|.||.|:.|::................:|:..  :||  ..|
plant   481 EFLSVDNNRIKDTFPFWLKALPNLQVLILSSNKLYGPIAPPHQSPLAFPELRIFE--IADNMFTG 543

  Fly   579 VFATLVSLLW----LNLSEN---HLVWFDYAF------------------------IPSNLKWLD 612
            ..:....:.|    |.::|:   ::|:.:.||                        :.::...:|
plant   544 TLSPRYFVNWKTSSLTVNEDGDLYMVYKNNAFGIDSYVYRDTIDMKYKGLSMEQQMVLNSYSAID 608

  Fly   613 IHGNYIEALGNYYK----LQEEIRVKTLDASHNRITEIGPMSIPNTIEL--LFINNNLIGNVQPN 671
            ..||.:|  |...|    |:|.|   .|:.|:|..|...|:|:.|..||  |.::.|.:....||
plant   609 FSGNRLE--GQIPKSIGLLKELI---ALNLSNNAFTCHIPLSLANATELESLDLSRNQLSGTIPN 668

  Fly   672 AFVDKANLARVDLYANQLSKLQLQQLRVAPVVAPKPL 708
            .....:.||.:::..|:|.....::.|:...:.| ||
plant   669 GLKTLSFLAYINVSHNKLKGENHKEHRLLGNINP-PL 704

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-7NP_523797.1 LRR_8 135..201 CDD:290566 20/62 (32%)
leucine-rich repeat 136..159 CDD:275380 6/20 (30%)
leucine-rich repeat 160..190 CDD:275380 10/29 (34%)
LRR_8 189..259 CDD:290566 15/70 (21%)
leucine-rich repeat 191..214 CDD:275380 8/23 (35%)
leucine-rich repeat 215..248 CDD:275380 1/32 (3%)
LRR_RI 247..501 CDD:238064 80/329 (24%)
LRR_8 247..308 CDD:290566 19/75 (25%)
leucine-rich repeat 249..273 CDD:275380 7/26 (27%)
leucine-rich repeat 274..297 CDD:275380 6/22 (27%)
LRR_8 297..356 CDD:290566 26/81 (32%)
leucine-rich repeat 298..321 CDD:275380 10/34 (29%)
leucine-rich repeat 322..345 CDD:275380 10/33 (30%)
LRR_8 345..406 CDD:290566 15/61 (25%)
leucine-rich repeat 346..371 CDD:275380 6/24 (25%)
leucine-rich repeat 372..395 CDD:275380 5/23 (22%)
leucine-rich repeat 396..419 CDD:275380 7/27 (26%)
LRR_8 419..478 CDD:290566 18/80 (23%)
leucine-rich repeat 420..443 CDD:275380 7/25 (28%)
leucine-rich repeat 444..467 CDD:275380 6/41 (15%)
LRR_RI 466..622 CDD:238064 42/210 (20%)
leucine-rich repeat 468..488 CDD:275380 6/20 (30%)
LRR_8 491..549 CDD:290566 20/57 (35%)
leucine-rich repeat 491..514 CDD:275380 9/22 (41%)
leucine-rich repeat 515..536 CDD:275380 4/20 (20%)
leucine-rich repeat 539..562 CDD:275380 5/22 (23%)
leucine-rich repeat 563..585 CDD:275380 4/23 (17%)
leucine-rich repeat 586..626 CDD:275380 11/70 (16%)
leucine-rich repeat 627..653 CDD:275380 9/25 (36%)
LRRCT 716..772 CDD:214507
LRRNT 796..830 CDD:214470
leucine-rich repeat 812..829 CDD:275380
leucine-rich repeat 833..854 CDD:275380
LRR_8 853..913 CDD:290566
leucine-rich repeat 855..878 CDD:275380
LRR_4 878..918 CDD:289563
leucine-rich repeat 879..902 CDD:275380
leucine-rich repeat 903..926 CDD:275380
leucine-rich repeat 927..953 CDD:275380
TIR 1098..1235 CDD:214587
RLP28NP_180867.1 LRR_8 101..161 CDD:290566 25/100 (25%)
leucine-rich repeat 102..126 CDD:275380 10/29 (34%)
LRR_RI <118..279 CDD:238064 53/200 (27%)
leucine-rich repeat 127..150 CDD:275380 10/57 (18%)
LRR_8 149..208 CDD:290566 18/63 (29%)
leucine-rich repeat 151..173 CDD:275380 7/26 (27%)
leucine-rich repeat 174..197 CDD:275380 6/22 (27%)
leucine-rich repeat 198..243 CDD:275380 11/44 (25%)
leucine-rich repeat 244..268 CDD:275380 8/23 (35%)
leucine-rich repeat 269..292 CDD:275380 7/25 (28%)
LRR_8 293..351 CDD:290566 15/62 (24%)
leucine-rich repeat 294..316 CDD:275380 4/21 (19%)
leucine-rich repeat 317..340 CDD:275380 7/27 (26%)
LRR_RI <332..514 CDD:238064 43/181 (24%)
leucine-rich repeat 432..455 CDD:275380 1/22 (5%)
LRR_8 455..514 CDD:290566 20/58 (34%)
leucine-rich repeat 456..479 CDD:275380 9/22 (41%)
leucine-rich repeat 480..501 CDD:275380 4/20 (20%)
leucine-rich repeat 531..603 CDD:275380 10/73 (14%)
leucine-rich repeat 604..627 CDD:275380 7/24 (29%)
leucine-rich repeat 628..651 CDD:275380 8/25 (32%)
leucine-rich repeat 652..675 CDD:275380 5/22 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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