Protein Alignment Toll-7 and Lrrc15

DIOPT Version :9

• Sequence 1: NP_523797.1
• Gene: Toll-7 / 37272
• FlyBaseID: FBgn0034476
• Length: 1446
• Species: Drosophila melanogaster
• Sequence 2: NP_083249.1
• Gene: Lrrc15 / 74488
• MGIID: 1921738
• Length: 579
• Species: Mus musculus
• Alignment Length: 432
• Identity: 133/432 - (30%)
• Similarity: 197/432 - (45%)
• Gaps: 30/432 - (6%)

  Fly   249 LQVLDASHNELRSISESWGISRLRRLQHLNLAYNNLSELSGEALAGLASLRIVNLSNNHLETLPE 313
            ||:|:....||.. .:...||.|..|:   :..|.|:.:...|...|.|||.::|:||.|:.||.
Mouse    58 LQILNTHITELPE-DKFLNISALIALK---MEKNELANIMPGAFRNLGSLRHLSLANNKLKNLPV 118

  Fly   314 GLFAGSKELREIHLQQNELYELPKGLFHRLEQLLVVDLSGNQLTSNHVDNTTFAGLIRLIVLNLA 378
            .||.....|..:.|..|:|.::....|.:...|..:.|.||.|  .::....|..|:.|..|||.
Mouse   119 RLFQDVNNLETLLLSNNQLVQIQPAQFSQFSNLKELQLYGNNL--EYIPEGVFDHLVGLTKLNLG 181

  Fly   379 HNALTRIDYRTFKELYFLQILNLRNNSIGHIEDNAFLPLYNLHTLNLAENRLHTLDDKLFNGLYV 443
            :|..|.:..|.|:.|..||:|.|..|.:..|....|..|.||..|.|.||::.||...||:....
Mouse   182 NNGFTHLSPRVFQHLGNLQVLRLYENRLSDIPMGTFDALGNLQELALQENQIGTLSPGLFHNNRN 246

  Fly   444 LSKLTLNNNLISVVEPAVFKNCSDLKELDLSSNQLNEV-PRALQDLAMLRTLDLGENQIRTFDNQ 507
            |.:|.|:||.||.:.|.:|.....|.:|.|..|.|.|: |.....:..||.|.|..|.|.:..:.
Mouse   247 LQRLYLSNNHISHLPPGIFMQLPHLNKLTLFGNSLKELSPGVFGPMPNLRELWLYNNHITSLPDN 311

  Fly   508 SFKNLHQLTGLRLIDNQIGNITVGMFQDLPRLSVLNLAKNRIQSIERGSFDKNFELEAIRLDRNF 572
            :|.:|:||..|.|..||:..|:.|.|..|..|..|:|..|.:|.::...|.....|..:.|..|.
Mouse   312 AFSHLNQLQVLILSHNQLSYISPGAFNGLTNLRELSLHTNALQDLDGNVFRSLANLRNVSLQNNR 376

  Fly   573 LADING-VFATLVSLLWLNLSENHLV-----WFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEI 631
            |..:.| :||.:..|:.:.|..|:|.     .||:.   .||..|.::.|......|...|.:.:
Mouse   377 LRQLPGSIFANVNGLMTIQLQNNNLENLPLGIFDHL---GNLCELRLYDNPWRCDSNILPLHDWL 438

  Fly   632 RVKTLDASHNRI---TEIGPM-SIPNTI---ELLFINNNLIG 666
            .:       ||.   |:..|: |.|.::   .|:.||.|..|
Mouse   439 IL-------NRARLGTDTLPVCSSPASVRGQSLVIINVNFPG 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-7	NP_523797.1	LRR_8	135..201	CDD:290566
		leucine-rich repeat	136..159	CDD:275380
		leucine-rich repeat	160..190	CDD:275380
		LRR_8	189..259	CDD:290566	3/9 (33%)
		leucine-rich repeat	191..214	CDD:275380
		leucine-rich repeat	215..248	CDD:275380
		LRR_RI	247..501	CDD:238064	84/252 (33%)
		LRR_8	247..308	CDD:290566	19/58 (33%)
		leucine-rich repeat	249..273	CDD:275380	8/23 (35%)
		leucine-rich repeat	274..297	CDD:275380	5/22 (23%)
		LRR_8	297..356	CDD:290566	20/58 (34%)
		leucine-rich repeat	298..321	CDD:275380	10/22 (45%)
		leucine-rich repeat	322..345	CDD:275380	5/22 (23%)
		LRR_8	345..406	CDD:290566	21/60 (35%)
		leucine-rich repeat	346..371	CDD:275380	7/24 (29%)
		leucine-rich repeat	372..395	CDD:275380	9/22 (41%)
		leucine-rich repeat	396..419	CDD:275380	8/22 (36%)
		LRR_8	419..478	CDD:290566	23/58 (40%)
		leucine-rich repeat	420..443	CDD:275380	9/22 (41%)
		leucine-rich repeat	444..467	CDD:275380	9/22 (41%)
		LRR_RI	466..622	CDD:238064	48/162 (30%)
		leucine-rich repeat	468..488	CDD:275380	7/20 (35%)
		LRR_8	491..549	CDD:290566	22/57 (39%)
		leucine-rich repeat	491..514	CDD:275380	8/22 (36%)
		leucine-rich repeat	515..536	CDD:275380	8/20 (40%)
		leucine-rich repeat	539..562	CDD:275380	6/22 (27%)
		leucine-rich repeat	563..585	CDD:275380	7/22 (32%)
		leucine-rich repeat	586..626	CDD:275380	11/44 (25%)
		leucine-rich repeat	627..653	CDD:275380	6/29 (21%)
		LRRCT	716..772	CDD:214507
		LRRNT	796..830	CDD:214470
		leucine-rich repeat	812..829	CDD:275380
		leucine-rich repeat	833..854	CDD:275380
		LRR_8	853..913	CDD:290566
		leucine-rich repeat	855..878	CDD:275380
		LRR_4	878..918	CDD:289563
		leucine-rich repeat	879..902	CDD:275380
		leucine-rich repeat	903..926	CDD:275380
		leucine-rich repeat	927..953	CDD:275380
		TIR	1098..1235	CDD:214587
Lrrc15	NP_083249.1	LRR 1	54..75		5/17 (29%)
		leucine-rich repeat	58..78	CDD:275380	6/20 (30%)
		LRR 2	78..99		5/23 (22%)
		PLN00113	82..>401	CDD:215061	105/323 (33%)
		LRR 3	102..123		11/20 (55%)
		leucine-rich repeat	103..126	CDD:275380	10/22 (45%)
		LRR 4	126..147		5/20 (25%)
		leucine-rich repeat	127..150	CDD:275380	5/22 (23%)
		LRR 5	150..171		6/22 (27%)
		leucine-rich repeat	151..174	CDD:275380	7/24 (29%)
		LRR 6	174..195		8/20 (40%)
		leucine-rich repeat	175..198	CDD:275380	9/22 (41%)
		LRR 7	198..219		7/20 (35%)
		leucine-rich repeat	199..222	CDD:275380	8/22 (36%)
		LRR 8	222..243		10/20 (50%)
		leucine-rich repeat	223..246	CDD:275380	9/22 (41%)
		LRR 9	246..267		9/20 (45%)
		leucine-rich repeat	247..270	CDD:275380	9/22 (41%)
		LRR 10	270..291		7/20 (35%)
		leucine-rich repeat	271..294	CDD:275380	7/22 (32%)
		LRR 11	294..315		7/20 (35%)
		leucine-rich repeat	295..318	CDD:275380	8/22 (36%)
		LRR 12	318..339		9/20 (45%)
		leucine-rich repeat	319..342	CDD:275380	9/22 (41%)
		LRR 13	342..363		6/20 (30%)
		leucine-rich repeat	343..364	CDD:275380	6/20 (30%)
		LRR 14	366..387		6/20 (30%)
		leucine-rich repeat	367..387	CDD:275380	6/19 (32%)
		LRR 15	390..411		5/20 (25%)
		leucine-rich repeat	391..412	CDD:275380	6/20 (30%)
		LRRCT	423..>462	CDD:214507	9/45 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..509

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010