Protein Alignment Toll-7 and lgi2a

DIOPT Version :9

• Sequence 1: NP_523797.1
• Gene: Toll-7 / 37272
• FlyBaseID: FBgn0034476
• Length: 1446
• Species: Drosophila melanogaster
• Sequence 2: NP_001034730.1
• Gene: lgi2a / 654827
• ZFINID: ZDB-GENE-060217-2
• Length: 536
• Species: Danio rerio
• Alignment Length: 591
• Identity: 115/591 - (19%)
• Similarity: 198/591 - (33%)
• Gaps: 222/591 - (37%)

  Fly   208 FLCPVGNLQVLNLTRNRIRTAEQMGFADMNCGAGS------GSA---------GSELQVLDASHN 257
            :|.|:||            ||::......:|....      ||:         .|.|.:::.:.:
Zfish    13 YLAPLGN------------TAKKAFKCPSSCSCSKESIICVGSSYVPRYIPNDVSSLSIVNGTFS 65

  Fly   258 ELRSISESWGISRLRRLQHLNLAYNNLSELSGEALAGLASLRIVNLSNNHLETLPEGLFAGSKEL 322
            |::...    .|.:..||.|.|..|.|:.:..:|.:||..|..:.:.||.:||..:..|.|.::|
Zfish    66 EVKEAM----FSHMPSLQLLLLNSNALTTVRDDAFSGLPHLEYLFIENNKIETTSKYSFRGLRDL 126

  Fly   323 REIHLQQNELYELPKGLFHRLEQLLVVDLSGN---------------QLTSNHVDNTTFAGLIRL 372
            ..:.|..|.:..||:.||..|:.|:.:||.||               :.|:..|.:...||
Zfish   127 THLSLANNNIKALPRELFIDLDSLIELDLRGNVFECDCRAKWLMMWLKSTNATVSDVLCAG---- 187

  Fly   373 IVLNLAHNALTRIDYRTFKELYFLQILNLRNNSIGHIEDNAFLPLYNLHTLNLAENRLHTLDDKL 437
                          ....|......:.:|.|..|    ...|:||:::.|.:|:   :.|...|
Zfish   188 --------------PEEMKGKRLNDMASLHNECI----STDFIPLHSVPTESLS---VDTFSHK- 230

  Fly   438 FNGLYVLSKLTLNNNLISVVEPAVFKNCSDLKELDLSSNQLNEVPRALQDLAMLRTLDLGENQIR 502
             |.:||           ::..|.. ::|                        |:...|..|...|
Zfish   231 -NDVYV-----------AIAAPNA-ESC------------------------MVLQWDHIEMNFR 258

  Fly   503 TFDNQSFKNLHQLTGLR--LIDNQIGNITVGMF---------QDLPRLSVLNLAKNRIQSIERGS 556
            |:||.:.::   :.|.:  :|.|::..|...:|         :|..:.|       :.|.||...
Zfish   259 TYDNITGQS---IVGCKSVIIQNEVFVIVAQLFGGSHIYKFDEDQSKFS-------KFQDIEVSK 313

  Fly   557 FDKNFELEAIRLDRNFLADINGVFATLVSLLWLNLSENHLVWF------DYAFIPSNLKWLDIHG 615
            ..|..::||.::..:                          ||      ..|.:.:..||.| .|
Zfish   314 ISKPNDIEAFQIGND--------------------------WFFIIADSSKAGLSTLYKWND-KG 351

  Fly   616 NYIEALGNYYKLQEEIR-----VKTLD-------ASHNRITEIGPMS-----------IPNTIEL 657
            .|     :|..|.|..|     ...||       ||.:::..|...|           |||..::
Zfish   352 FY-----SYQSLHEWFRDTDAEFVNLDGKAHLILASRSQVPVIYQWSRSTQKFTLQGEIPNMEDV 411

  Fly   658 LFINNNLIGNVQPNAFVDKANLARVDLY----------------ANQLSKLQLQQLRVAPVVAPK 706
            :.:               ||...:.|||                |.:.|::|....|.:.::.|.
Zfish   412 VAV---------------KAFWIKEDLYLAMTRYIGDSKVLHWTAKEFSEVQAIPSRGSMILQPF 461

  Fly   707 PLPEFY 712
            ...|.|
Zfish   462 SFKERY 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-7	NP_523797.1	LRR_8	135..201	CDD:290566
		leucine-rich repeat	136..159	CDD:275380
		leucine-rich repeat	160..190	CDD:275380
		LRR_8	189..259	CDD:290566	11/65 (17%)
		leucine-rich repeat	191..214	CDD:275380	2/5 (40%)
		leucine-rich repeat	215..248	CDD:275380	5/47 (11%)
		LRR_RI	247..501	CDD:238064	56/268 (21%)
		LRR_8	247..308	CDD:290566	16/60 (27%)
		leucine-rich repeat	249..273	CDD:275380	3/23 (13%)
		leucine-rich repeat	274..297	CDD:275380	9/22 (41%)
		LRR_8	297..356	CDD:290566	20/73 (27%)
		leucine-rich repeat	298..321	CDD:275380	7/22 (32%)
		leucine-rich repeat	322..345	CDD:275380	8/22 (36%)
		LRR_8	345..406	CDD:290566	12/75 (16%)
		leucine-rich repeat	346..371	CDD:275380	9/39 (23%)
		leucine-rich repeat	372..395	CDD:275380	1/22 (5%)
		leucine-rich repeat	396..419	CDD:275380	6/22 (27%)
		LRR_8	419..478	CDD:290566	9/58 (16%)
		leucine-rich repeat	420..443	CDD:275380	5/22 (23%)
		leucine-rich repeat	444..467	CDD:275380	2/22 (9%)
		LRR_RI	466..622	CDD:238064	28/172 (16%)
		leucine-rich repeat	468..488	CDD:275380	0/19 (0%)
		LRR_8	491..549	CDD:290566	13/68 (19%)
		leucine-rich repeat	491..514	CDD:275380	6/22 (27%)
		leucine-rich repeat	515..536	CDD:275380	5/31 (16%)
		leucine-rich repeat	539..562	CDD:275380	5/22 (23%)
		leucine-rich repeat	563..585	CDD:275380	2/21 (10%)
		leucine-rich repeat	586..626	CDD:275380	9/45 (20%)
		leucine-rich repeat	627..653	CDD:275380	10/48 (21%)
		LRRCT	716..772	CDD:214507
		LRRNT	796..830	CDD:214470
		leucine-rich repeat	812..829	CDD:275380
		leucine-rich repeat	833..854	CDD:275380
		LRR_8	853..913	CDD:290566
		leucine-rich repeat	855..878	CDD:275380
		LRR_4	878..918	CDD:289563
		leucine-rich repeat	879..902	CDD:275380
		leucine-rich repeat	903..926	CDD:275380
		leucine-rich repeat	927..953	CDD:275380
		TIR	1098..1235	CDD:214587
lgi2a	NP_001034730.1	LRR_8	54..112	CDD:290566	16/61 (26%)
		LRR_8	100..158	CDD:290566	18/57 (32%)
		LRR_4	100..140	CDD:289563	10/39 (26%)
		leucine-rich repeat	102..125	CDD:275378	7/22 (32%)
		LRR_4	126..>158	CDD:289563	11/31 (35%)
		leucine-rich repeat	126..149	CDD:275378	8/22 (36%)
		leucine-rich repeat	150..162	CDD:275378	5/11 (45%)
		LRRCT	158..198	CDD:214507	6/57 (11%)
		EPTP	210..251	CDD:281697	13/81 (16%)
		EPTP	257..297	CDD:281697	9/42 (21%)
		EPTP	302..348	CDD:281697	11/78 (14%)
		EPTP	351..393	CDD:281697	11/46 (24%)
		EPTP	398..439	CDD:281697	8/55 (15%)
		EPTP	443..484	CDD:281697	6/25 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000