DRSC/TRiP Functional Genomics Resources

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Protein Alignment Toll-7 and tsku

DIOPT Version :9

Sequence 1:NP_523797.1 Gene:Toll-7 / 37272 FlyBaseID:FBgn0034476 Length:1446 Species:Drosophila melanogaster
Sequence 2:NP_956027.2 Gene:tsku / 325958 ZFINID:ZDB-GENE-030131-4683 Length:366 Species:Danio rerio


Alignment Length:305 Identity:91/305 - (29%)
Similarity:141/305 - (46%) Gaps:66/305 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   252 LDASHNELRSISESW----GISRLRRLQHLNLAYNNLSELSGEALAGLASLRIVNLSNNHLETLP 312
            ||.|.|.:.|||::.    |.:   .|..|:|:.|.::::|.:|.:.|..|..::||:|.||.|.
Zfish    85 LDLSLNSITSISDTMLSGPGYT---TLVSLDLSSNLIAQISPKAFSKLRYLETLDLSSNALEGLS 146

  Fly   313 EGLFAGSKELREIHLQQNELYELPKGLFHRLEQLLVVDLSGNQLTSNHVDNTTFAGLIRLIVLNL 377
            :|.|.|                ||         |:.:|||.||....::|..|.......|:::|
Zfish   147 DGCFTG----------------LP---------LVELDLSENQFKEFNLDLFTTRTQDLPIMVDL 186

  Fly   378 AHNALTRIDYRTFKELYFLQILNLRNNSIGHIEDNAFLPLYNLHTLNLAENRLHTLDDKLFNGLY 442
            :.|.||.|..||                .||       ||| :.:|.||.|:|.|: .|| ||: 
Zfish   187 SRNLLTSIFRRT----------------PGH-------PLY-IKSLMLAGNQLKTV-PKL-NGI- 224

  Fly   443 VLSKLTLNNNLISVVEPAVFKNCSDLKELDLSSNQLNEV----PRALQDLAMLRTLDLGEN-QIR 502
            .|..|.|:.||||.::...|.:.::|..|.||.  |:|:    |.|.:.|..|:.|||..| |::
Zfish   225 PLQYLNLDGNLISSIDTGAFDSLTELVHLSLSG--LSELTLIHPGAFRSLKNLQALDLSNNSQLK 287

  Fly   503 TFDNQSFKNLHQLTGLRLIDNQIGNITVGMFQDLPRLSVLNLAKN 547
            |.:...|..|..|..|.|.:..:..::..:|..:|.:..:.|..|
Zfish   288 TLNPDVFSGLVSLQELNLSNTAVTPLSRTVFMQMPNIKSITLGPN 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-7NP_523797.1 LRR_8 135..201 CDD:290566
leucine-rich repeat 136..159 CDD:275380
leucine-rich repeat 160..190 CDD:275380
LRR_8 189..259 CDD:290566 4/6 (67%)
leucine-rich repeat 191..214 CDD:275380
leucine-rich repeat 215..248 CDD:275380
LRR_RI 247..501 CDD:238064 80/257 (31%)
LRR_8 247..308 CDD:290566 19/59 (32%)
leucine-rich repeat 249..273 CDD:275380 8/24 (33%)
leucine-rich repeat 274..297 CDD:275380 7/22 (32%)
LRR_8 297..356 CDD:290566 17/58 (29%)
leucine-rich repeat 298..321 CDD:275380 10/22 (45%)
leucine-rich repeat 322..345 CDD:275380 2/22 (9%)
LRR_8 345..406 CDD:290566 16/60 (27%)
leucine-rich repeat 346..371 CDD:275380 8/24 (33%)
leucine-rich repeat 372..395 CDD:275380 8/22 (36%)
leucine-rich repeat 396..419 CDD:275380 4/22 (18%)
LRR_8 419..478 CDD:290566 22/58 (38%)
leucine-rich repeat 420..443 CDD:275380 10/22 (45%)
leucine-rich repeat 444..467 CDD:275380 8/22 (36%)
LRR_RI 466..622 CDD:238064 25/87 (29%)
leucine-rich repeat 468..488 CDD:275380 8/23 (35%)
LRR_8 491..549 CDD:290566 16/58 (28%)
leucine-rich repeat 491..514 CDD:275380 9/23 (39%)
leucine-rich repeat 515..536 CDD:275380 4/20 (20%)
leucine-rich repeat 539..562 CDD:275380 2/9 (22%)
leucine-rich repeat 563..585 CDD:275380
leucine-rich repeat 586..626 CDD:275380
leucine-rich repeat 627..653 CDD:275380
LRRCT 716..772 CDD:214507
LRRNT 796..830 CDD:214470
leucine-rich repeat 812..829 CDD:275380
leucine-rich repeat 833..854 CDD:275380
LRR_8 853..913 CDD:290566
leucine-rich repeat 855..878 CDD:275380
LRR_4 878..918 CDD:289563
leucine-rich repeat 879..902 CDD:275380
leucine-rich repeat 903..926 CDD:275380
leucine-rich repeat 927..953 CDD:275380
TIR 1098..1235 CDD:214587
tskuNP_956027.2 leucine-rich repeat 82..107 CDD:275380 8/24 (33%)
LRR_8 106..165 CDD:290566 24/86 (28%)
LRR_RI 108..311 CDD:238064 79/256 (31%)
leucine-rich repeat 108..131 CDD:275380 7/22 (32%)
leucine-rich repeat 132..153 CDD:275380 10/36 (28%)
leucine-rich repeat 155..176 CDD:275380 8/20 (40%)
leucine-rich repeat 177..220 CDD:275380 19/67 (28%)
LRR_8 206..257 CDD:290566 21/53 (40%)
leucine-rich repeat 226..249 CDD:275380 8/22 (36%)
LRR_8 248..308 CDD:290566 21/61 (34%)
leucine-rich repeat 250..274 CDD:275380 9/25 (36%)
leucine-rich repeat 275..299 CDD:275380 9/23 (39%)
leucine-rich repeat 300..323 CDD:275380 4/22 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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