DRSC/TRiP Functional Genomics Resources

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Protein Alignment Toll-7 and LOC100535105

DIOPT Version :9

Sequence 1:NP_523797.1 Gene:Toll-7 / 37272 FlyBaseID:FBgn0034476 Length:1446 Species:Drosophila melanogaster
Sequence 2:XP_009298331.1 Gene:LOC100535105 / 100535105 -ID:- Length:706 Species:Danio rerio


Alignment Length:448 Identity:109/448 - (24%)
Similarity:170/448 - (37%) Gaps:114/448 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   338 GLFHRLEQLLVVDLSGNQLTSNHVDNTTFAGLIRLIVLNLAHNALTRIDYRTFKELYFLQILNLR 402
            ||| :|...|.:|.....|.:|                |:|.|. ..:||.|     .:..::|.
Zfish    59 GLF-KLPTRLPLDTQVLLLQTN----------------NIAKNE-HPLDYLT-----NITEIDLS 100

  Fly   403 NNSIGHIEDNAFLPLYNLHTLNLAENRLHTLDDKLFNGLYVLSKLTLNNNLISVVEPAVFKNCSD 467
            .|::..|.|.....|..|.:|::.||.:.:|.|...:.|..|.:|.||:||||::.|..|:....
Zfish   101 QNNLSSINDINIGSLPQLLSLHMEENWICSLPDNSLSQLTNLQELYLNHNLISLISPEAFRGLQS 165

  Fly   468 LKELDLSSNQLNEVPRA-LQDLAMLRTLDLGENQIRTFDNQSFKNLHQLTGLRLIDNQIGNITVG 531
            |..|.|:||:|..:... .:.|..|..|.:|||.:.:..:.:||.|..|..|.|....:..|...
Zfish   166 LLRLHLNSNRLQIIKSEWFEPLPNLEILMIGENPVLSIQDMNFKPLRNLRSLVLTRMNLSQIPDD 230

  Fly   532 MFQDLPRLSVLNLAKNRIQSIERGSFDKNFELEAIRLDRNFLADINGVFATLVSLLWLNLSENHL 596
            .|..|..|..::...|....:..|         |:|                           ||
Zfish   231 SFLGLDNLESISFYDNTFPKVPHG---------ALR---------------------------HL 259

  Fly   597 VWFDYAFIPSNLKWLDIHGNYIEAL--GNYYKLQEEIRVKTLDASHNRITEIGPMSIPNTIEL-L 658
                     .:||:||::.|.|..:  |::           :|..|  :.|:|..|:|..:.: .
Zfish   260 ---------KSLKFLDLNKNPIGRIQRGDF-----------VDMLH--LKELGINSMPELVSIDS 302

  Fly   659 FINNNL-------------IGNVQPNAFVDKANLARVDLYANQLSKLQLQQLRVAPVVAPKPLPE 710
            |..|||             :..:.||||.....|..:.|..|.||.|.    |:.....|. |.|
Zfish   303 FALNNLPELTKIEATNNPKLSYIHPNAFYRLPRLETLMLNGNALSALH----RITVESLPN-LRE 362

  Fly   711 FYLGGNPFECDCTMDWLQRINNLTTRQHPRVMDMANIECVMP------HARGAAVRPL 762
            ..:..||..|||.:.|:.     ..:.:.|.|:..::.||.|      |.|....|.:
Zfish   363 VSMHSNPIRCDCVVRWMN-----MNKTNIRFMEPDSLFCVEPPEYEGQHVRQVHFREM 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-7NP_523797.1 LRR_8 135..201 CDD:290566
leucine-rich repeat 136..159 CDD:275380
leucine-rich repeat 160..190 CDD:275380
LRR_8 189..259 CDD:290566
leucine-rich repeat 191..214 CDD:275380
leucine-rich repeat 215..248 CDD:275380
LRR_RI 247..501 CDD:238064 48/163 (29%)
LRR_8 247..308 CDD:290566
leucine-rich repeat 249..273 CDD:275380
leucine-rich repeat 274..297 CDD:275380
LRR_8 297..356 CDD:290566 6/17 (35%)
leucine-rich repeat 298..321 CDD:275380
leucine-rich repeat 322..345 CDD:275380 4/6 (67%)
LRR_8 345..406 CDD:290566 12/60 (20%)
leucine-rich repeat 346..371 CDD:275380 4/24 (17%)
leucine-rich repeat 372..395 CDD:275380 6/22 (27%)
leucine-rich repeat 396..419 CDD:275380 5/22 (23%)
LRR_8 419..478 CDD:290566 22/58 (38%)
leucine-rich repeat 420..443 CDD:275380 7/22 (32%)
leucine-rich repeat 444..467 CDD:275380 10/22 (45%)
LRR_RI 466..622 CDD:238064 34/158 (22%)
leucine-rich repeat 468..488 CDD:275380 6/20 (30%)
LRR_8 491..549 CDD:290566 16/57 (28%)
leucine-rich repeat 491..514 CDD:275380 8/22 (36%)
leucine-rich repeat 515..536 CDD:275380 5/20 (25%)
leucine-rich repeat 539..562 CDD:275380 3/22 (14%)
leucine-rich repeat 563..585 CDD:275380 2/21 (10%)
leucine-rich repeat 586..626 CDD:275380 9/41 (22%)
leucine-rich repeat 627..653 CDD:275380 5/25 (20%)
LRRCT 716..772 CDD:214507 14/53 (26%)
LRRNT 796..830 CDD:214470
leucine-rich repeat 812..829 CDD:275380
leucine-rich repeat 833..854 CDD:275380
LRR_8 853..913 CDD:290566
leucine-rich repeat 855..878 CDD:275380
LRR_4 878..918 CDD:289563
leucine-rich repeat 879..902 CDD:275380
leucine-rich repeat 903..926 CDD:275380
leucine-rich repeat 927..953 CDD:275380
TIR 1098..1235 CDD:214587
LOC100535105XP_009298331.1 leucine-rich repeat 52..70 CDD:275380 5/11 (45%)
leucine-rich repeat 71..93 CDD:275380 8/43 (19%)
LRR_RI 88..>273 CDD:238064 58/234 (25%)
leucine-rich repeat 95..117 CDD:275380 5/21 (24%)
LRR_8 116..176 CDD:290566 22/59 (37%)
leucine-rich repeat 118..141 CDD:275380 7/22 (32%)
leucine-rich repeat 142..165 CDD:275380 10/22 (45%)
LRR_8 165..221 CDD:290566 18/55 (33%)
leucine-rich repeat 166..189 CDD:275380 7/22 (32%)
leucine-rich repeat 190..213 CDD:275380 8/22 (36%)
LRR_8 212..272 CDD:290566 18/104 (17%)
leucine-rich repeat 214..237 CDD:275380 6/22 (27%)
leucine-rich repeat 238..261 CDD:275380 7/67 (10%)
leucine-rich repeat 262..285 CDD:275380 8/33 (24%)
leucine-rich repeat 286..310 CDD:275380 8/23 (35%)
LRR_8 309..370 CDD:290566 15/65 (23%)
leucine-rich repeat 311..333 CDD:275380 4/21 (19%)
leucine-rich repeat 336..357 CDD:275380 7/24 (29%)
leucine-rich repeat 360..372 CDD:275378 4/11 (36%)
LRRCT 368..411 CDD:214507 13/47 (28%)
IG_like 429..513 CDD:214653
Ig 437..513 CDD:299845
fn3 518..593 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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