Protein Alignment Toll-7 and lrrtm4

DIOPT Version :10

• Sequence 1: NP_523797.1
• Gene: Toll-7 / 37272
• FlyBaseID: FBgn0034476
• Length: 1446
• Species: Drosophila melanogaster
• Sequence 2: XP_031755133.1
• Gene: lrrtm4 / 100485215
• XenbaseID: XB-GENE-949702
• Length: 622
• Species: Xenopus tropicalis
• Alignment Length: 420
• Identity: 111/420 - (26%)
• Similarity: 177/420 - (42%)
• Gaps: 86/420 - (20%)

  Fly   299 RIVNLSNNHLETLPEGLFAGSKELREIHLQQNELYELPKGLFHRLEQLLVVDLSGNQLTSNHVDN 363
            :||...::....:|:.:..||:.|   .|:.|.:                      ::..:|
 Frog    43 KIVYCESHAFRDIPQNISGGSQGL---SLRYNSI----------------------KMLKSH--- 79

  Fly   364 TTFAGLIRLIVLNLAHNALTRIDYRTFKELYFLQILNLRNNSIGHIEDNAFLPLYNLHTLNLAEN 428
             .|:||.:|:.|.|.||.::.:|...|:.:..|:.|.|.:|.|.::.::.|.|:.||..|:|:.|
 Frog    80 -QFSGLNQLVWLYLDHNYISTVDEDAFQGIRRLKELILSSNKISYLGNSTFHPVPNLRNLDLSYN 143

  Fly   429 RLHTLDDKLFNGLYVLSKLTLNNNLISVVEPAVFKNCSDLKELDLSSNQLNEVPR-ALQDLAMLR 492
            :|.||..:.|.||..|..|.|.:|.:..|...||::|.:|..|||..|:|..:.| |...|..|:
 Frog   144 KLQTLQSEQFKGLRKLLILHLRSNSLKTVPVRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLK 208

  Fly   493 TLDLGENQIRTFDNQSFKNLHQLTGLRLIDNQIGNITVGMFQDLPRLSVLNLAKNRIQSIERGSF 557
            .|.|..||....:...|..|..|..|.|..|:|.:|:.|:......|..|:|:.|.||::|.|:|
 Frog   209 ELHLEHNQFSKVNFAHFPRLFNLRSLYLQWNKIRSISQGLTWTWSALQNLDLSGNDIQNLEPGTF 273

  Fly   558 DKNFELEAIRLDRNFLADINGVFATL---VSLLWLNLSENHLVWFDYAFIPSNLKWL-DIHGNYI 618
            .....|:.:.||.|.|.::..  .||   :||..:.||.|  :|.....|...:.|| :..||
 Frog   274 QCLPNLQKLNLDSNKLTNVTQ--ETLNAWISLTSITLSGN--IWECTKKICPLVFWLKNFKGN-- 332

  Fly   619 EALGNYYKLQEEIRVKTLDASHNRITEIGPMSIPNTIELLFINNNLIGNVQPNAFVDKANLARVD 683
                     :|.|.:               .:.|.             |:|.....|     .|:
 Frog   333 ---------KESIMI---------------CASPK-------------NMQGEKVTD-----AVE 355

  Fly   684 LY--ANQLSKLQLQQLRVAPVVAPKPLPEF 711
            .|  .|:...|..:  |..|...|.|.|:|
 Frog   356 TYNICNETPVLATE--RAYPTTKPPPKPQF 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-7	NP_523797.1	LRR	45..473	CDD:443914	47/173 (27%)
		leucine-rich repeat	136..159	CDD:275380
		leucine-rich repeat	160..190	CDD:275380
		leucine-rich repeat	191..214	CDD:275380
		leucine-rich repeat	215..248	CDD:275380
		leucine-rich repeat	249..273	CDD:275380
		leucine-rich repeat	274..297	CDD:275380
		leucine-rich repeat	298..321	CDD:275380	5/21 (24%)
		leucine-rich repeat	322..345	CDD:275380	3/22 (14%)
		leucine-rich repeat	346..371	CDD:275380	4/24 (17%)
		LRR	369..>675	CDD:443914	89/310 (29%)
		leucine-rich repeat	372..395	CDD:275380	7/22 (32%)
		leucine-rich repeat	396..419	CDD:275380	7/22 (32%)
		leucine-rich repeat	420..443	CDD:275380	10/22 (45%)
		leucine-rich repeat	444..467	CDD:275380	8/22 (36%)
		leucine-rich repeat	468..488	CDD:275380	8/20 (40%)
		leucine-rich repeat	491..514	CDD:275380	7/22 (32%)
		leucine-rich repeat	515..536	CDD:275380	7/20 (35%)
		leucine-rich repeat	539..562	CDD:275380	9/22 (41%)
		leucine-rich repeat	563..585	CDD:275380	7/24 (29%)
		leucine-rich repeat	586..626	CDD:275380	10/40 (25%)
		leucine-rich repeat	627..653	CDD:275380	2/25 (8%)
		LRRCT	716..772	CDD:214507
		LRR	<812..>963	CDD:443914
		leucine-rich repeat	812..829	CDD:275380
		leucine-rich repeat	833..854	CDD:275380
		leucine-rich repeat	855..878	CDD:275380
		leucine-rich repeat	879..902	CDD:275380
		leucine-rich repeat	903..926	CDD:275380
		leucine-rich repeat	927..953	CDD:275380
		TIR	1098..1235	CDD:214587
lrrtm4	XP_031755133.1	leucine-rich repeat	43..61	CDD:275380	3/17 (18%)
		leucine-rich repeat	64..86	CDD:275380	7/50 (14%)
		LRR	<81..>312	CDD:443914	80/234 (34%)
		leucine-rich repeat	87..110	CDD:275380	7/22 (32%)
		leucine-rich repeat	111..134	CDD:275380	7/22 (32%)
		leucine-rich repeat	135..158	CDD:275380	10/22 (45%)
		leucine-rich repeat	159..182	CDD:275380	8/22 (36%)
		leucine-rich repeat	183..206	CDD:275380	9/22 (41%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		leucine-rich repeat	231..254	CDD:275380	7/22 (32%)
		leucine-rich repeat	255..278	CDD:275380	9/22 (41%)
		leucine-rich repeat	279..297	CDD:275380	5/19 (26%)
		leucine-rich repeat	303..315	CDD:275378	5/13 (38%)