Protein Alignment Toll-7 and si:ch211-180f4.1

DIOPT Version :9

• Sequence 1: NP_523797.1
• Gene: Toll-7 / 37272
• FlyBaseID: FBgn0034476
• Length: 1446
• Species: Drosophila melanogaster
• Sequence 2: NP_001373634.1
• Gene: si:ch211-180f4.1 / 100144405
• ZFINID: ZDB-GENE-080327-27
• Length: 744
• Species: Danio rerio
• Alignment Length: 545
• Identity: 140/545 - (25%)
• Similarity: 218/545 - (40%)
• Gaps: 113/545 - (20%)

  Fly   257 NELRSISESWGISRLRRLQHLNLAYNNLSELSGEALAGLASLRIVNLSNNHLETLPEGLFAGSKE 321
            |||......|.||  ...|.|.|..||:|..:.: |..|.:|..::||.||...:.:.......:
Zfish    56 NELHLSRIPWNIS--VDTQVLLLQSNNISRGTSQ-LQSLVNLTELDLSQNHFTQIHDVGLNNLTQ 117

  Fly   322 LREIHLQQNELYELPKGLFHRLEQLLVVDLSGNQLTSNHVDNTTFAGLIRLIVLNLAHNALTRID 386
            |..::|::|::.|||......|..|..:.::.||::|  :....|:||..|:.|:|..|.|..||
Zfish   118 LVTLYLEENQIKELPDMCLKDLVSLEELYINHNQISS--IGPNAFSGLGNLLRLHLNSNKLVAID 180

  Fly   387 YRTFKELYFLQILNLRNNSIGHIEDNAFLPLYNLHTLNLAENRLHTLDDKLFNGLYVLSKLTLNN 451
            ...|:.|..|:||.:..|.|..::|..|.||..||:|.||...|..:.:..|.||
Zfish   181 SHWFESLPNLEILMIGENPILGLQDMNFHPLTKLHSLVLAGMGLREIPEGAFQGL---------- 235

  Fly   452 NLISVVEPAVFKNCSDLKELDLSSNQLNEVP-RALQDLAMLRTLDLGENQIRTFDNQSFKNLHQL 515
                          ..|:.|....|:|..|| :||:.|..|:.|||.:
Zfish   236 --------------EYLESLSFFDNKLTAVPKKALRVLPSLKFLDLNK----------------- 269

  Fly   516 TGLRLIDNQIGNITVGMFQDLPRLSVLNLAK-NRIQSIERGSFDKNFELEAIRLDRN---FLADI 576
                   |.|..|..|.|||.|.|..|:|.. ..:.::|||||....::..:.|..|   |..|
Zfish   270 -------NPIVRIQEGDFQDFPHLEELSLNNMEELVAVERGSFSNLPQMAKLELYNNPHLFFID- 326

  Fly   577 NGVFATLVSLLWLNLSENHLVWFDYAFIPS--NLKWLDIHGNYIE---------ALGNYYKLQEE 630
            ...|..:..|..|.:..|.|....:..:.:  ||..:.:|.|.:.         .|||    |..
Zfish   327 RAAFLKMRGLRTLLIHNNDLTLLPHEIVSAFPNLDEISLHSNPLRCDCLNNWGPVLGN----QSS 387

  Fly   631 IRVK----TLDASHNRITEIGPMSIPNTIELLF--INNNLIGNVQPNAFVDKANLARVDLYANQL 689
            ::|.    ||.||...:  :| .::.:.:...:  .:|..:..:..:||..:.|:....|
Zfish   388 LKVLEPQITLCASPQHL--VG-QALQDVVSASWNGASNTCLPLISQHAFPPQLNVTLGQL----- 444

  Fly   690 SKLQLQQLRVAPVVAPKPLPEFYLGGNPFECDCTMDWLQRINNL---TTRQHPRVMDMANIE--- 748
              |.|....||     .|.|:|| ...|.....|.:.:...:|.   |.::| |:.|...:|
Zfish   445 --LTLDCWAVA-----DPAPQFY-WVTPTGDKVTSEAVSPSSNEGGGTPKKH-RMQDQGALEIPH 500

  Fly   749 ----------CVMPHARGAAVRPLS 763
                      ||..:|.||..|.:|
Zfish   501 IEPEDTGLYTCVAWNAEGADTRSVS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-7	NP_523797.1	LRR_8	135..201	CDD:290566
		leucine-rich repeat	136..159	CDD:275380
		leucine-rich repeat	160..190	CDD:275380
		LRR_8	189..259	CDD:290566	1/1 (100%)
		leucine-rich repeat	191..214	CDD:275380
		leucine-rich repeat	215..248	CDD:275380
		LRR_RI	247..501	CDD:238064	73/244 (30%)
		LRR_8	247..308	CDD:290566	18/50 (36%)
		leucine-rich repeat	249..273	CDD:275380	6/15 (40%)
		leucine-rich repeat	274..297	CDD:275380	8/22 (36%)
		LRR_8	297..356	CDD:290566	14/58 (24%)
		leucine-rich repeat	298..321	CDD:275380	5/22 (23%)
		leucine-rich repeat	322..345	CDD:275380	7/22 (32%)
		LRR_8	345..406	CDD:290566	20/60 (33%)
		leucine-rich repeat	346..371	CDD:275380	7/24 (29%)
		leucine-rich repeat	372..395	CDD:275380	9/22 (41%)
		leucine-rich repeat	396..419	CDD:275380	9/22 (41%)
		LRR_8	419..478	CDD:290566	12/58 (21%)
		leucine-rich repeat	420..443	CDD:275380	9/22 (41%)
		leucine-rich repeat	444..467	CDD:275380	0/22 (0%)
		LRR_RI	466..622	CDD:238064	42/171 (25%)
		leucine-rich repeat	468..488	CDD:275380	8/20 (40%)
		LRR_8	491..549	CDD:290566	15/58 (26%)
		leucine-rich repeat	491..514	CDD:275380	4/22 (18%)
		leucine-rich repeat	515..536	CDD:275380	6/20 (30%)
		leucine-rich repeat	539..562	CDD:275380	8/23 (35%)
		leucine-rich repeat	563..585	CDD:275380	5/24 (21%)
		leucine-rich repeat	586..626	CDD:275380	11/50 (22%)
		leucine-rich repeat	627..653	CDD:275380	7/29 (24%)
		LRRCT	716..772	CDD:214507	15/64 (23%)
		LRRNT	796..830	CDD:214470
		leucine-rich repeat	812..829	CDD:275380
		leucine-rich repeat	833..854	CDD:275380
		LRR_8	853..913	CDD:290566
		leucine-rich repeat	855..878	CDD:275380
		LRR_4	878..918	CDD:289563
		leucine-rich repeat	879..902	CDD:275380
		leucine-rich repeat	903..926	CDD:275380
		leucine-rich repeat	927..953	CDD:275380
		TIR	1098..1235	CDD:214587
si:ch211-180f4.1	NP_001373634.1	leucine-rich repeat	51..70	CDD:275380	6/15 (40%)
		PPP1R42	55..266	CDD:411060	70/238 (29%)
		leucine-rich repeat	71..93	CDD:275380	8/22 (36%)
		leucine-rich repeat	94..117	CDD:275380	5/22 (23%)
		leucine-rich repeat	118..141	CDD:275380	7/22 (32%)
		leucine-rich repeat	142..165	CDD:275380	7/24 (29%)
		leucine-rich repeat	166..189	CDD:275380	9/22 (41%)
		leucine-rich repeat	190..213	CDD:275380	9/22 (41%)
		leucine-rich repeat	214..237	CDD:275380	9/46 (20%)
		leucine-rich repeat	238..261	CDD:275380	9/22 (41%)
		LRR_8	260..320	CDD:404697	21/83 (25%)
		leucine-rich repeat	262..285	CDD:275380	11/46 (24%)
		leucine-rich repeat	286..310	CDD:275380	8/23 (35%)
		leucine-rich repeat	311..330	CDD:275380	4/19 (21%)
		leucine-rich repeat	336..359	CDD:275378	4/22 (18%)
		PCC	341..>412	CDD:188093	16/77 (21%)
		leucine-rich repeat	360..372	CDD:275378	3/11 (27%)
		IG	434..528	CDD:214652	25/106 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010