Protein Alignment sm and PABPC4

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001129125.1
• Gene: PABPC4 / 8761
• HGNCID: 8557
• Length: 660
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 98/533 - (18%)
• Similarity: 159/533 - (29%)
• Gaps: 226/533 - (42%)

  Fly    99 LHKICHPHGQVLRIVIFK-KNGVQ---AMVEFDNLDAATRARENLNGAD-----IYAGCCTLKI- 153
            |.::....|:.|.:.:.: .||..   ..|.::..:.|.:|.|.:||.:     |:.|....|:
Human   207 LKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271

  Fly   154 ---------DYAKPEKLNVY-------KNEPDTSWDYTL-----------STVKEIGNGRSP--- 188
                     :..|.|:::.|       ||..||..|..|           |....:.:|||.
Human   272 RQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFG 336

  Fly   189 ---------------------LLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPH 232
                                 :..:|||||.....::..:|..:.::
Human   337 FVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYM------------------ 383

  Fly   233 PQHLHHQQQLVAPAQSHNLYQFKEPPLLGPGAAFPPF-----GAPEYHTTT-------------- 278
             |.:...:.|.|.|   .|.||:.    ..|..|.|.     |.|.|:|..
Human   384 -QRVAGMRALPANA---ILNQFQP----AAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQG 440

  Fly   279 --PENWKG--AAIHPTGLMKEPAGVVPGRNAPVA---------------------FTPQGQAQGA 318
              |:.::|  :||..:|.......:.|..|||.:                     |...|.||
Human   441 GRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGSECPDRLAMDFGGAGAAQ-- 503

  Fly   319 VMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQHLNNIPVGTG 383
                .||      ||.     |..|.|.          ||:..:....||......
Human   504 ----QGL------TDS-----CQSGGVP----------TAVQNLAPRAAVAAAAPR--------- 534

  Fly   384 GKIQIAFSKQNFLSEVINPF--LLPDHSPSFKEYTGSKNNRFLSPAQASKNRIQPPSKILHFFNT 446
                 |.:...:.|.|.:|.  :.|..:|....:...:     .|..||.....||.:
Human   535 -----AVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQ-----EPLTASMLAAAPPQE------- 582

  Fly   447 PPGLTEDQLIGIFNIKDVPATSVRLFPL-KTERSSSG------LIEFSN---------------- 488
                 :.|::|           .||||| :|..|:..      |:|..|
Human   583 -----QKQMLG-----------ERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSK 631

  Fly   489 ISQAVLAIMKCNH 501
            :.:|| |:::.:|
Human   632 VDEAV-AVLQAHH 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	17/91 (19%)
		RRM3_hnRNPL_like	319..390	CDD:240870	11/70 (16%)
		RRM4_hnRNPL_like	437..519	CDD:240873	17/88 (19%)
PABPC4	NP_001129125.1	PABP-1234	11..640	CDD:130689	97/528 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000