DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sm and PTB3

DIOPT Version :9

Sequence 1:	NP_001246428.1	Gene:	sm / 37254	FlyBaseID:	FBgn0003435	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001077672.1	Gene:	PTB3 / 840918	AraportID:	AT1G43190	Length:	432	Species:	Arabidopsis thaliana

Alignment Length:	450	Identity:	122/450 - (27%)
Similarity:	190/450 - (42%)	Gaps:	117/450 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 PNHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIFKKN-GVQAMVEFDNLDAATRARENLNGA 142
            ||.|||.||.:..|||||||||::..|:|.|.::|.|:|: |.||::::.....|..||..|.|.
plant    97 PNRILLVTIHHMLYPITVDVLHQVFSPYGFVEKLVTFQKSAGFQALIQYQVQQCAASARTALQGR 161

  Fly   143 DIYAGCCTLKIDYAKPEKLNV-YKNEPDTSWDYTLSTVKEIGNGRSPLLQEPLYVATLSTPQQHV 206
            :||.|||.|.|.::..|:|.| |.|  |.|.|||...:.....|||   ..|.|..|
plant   162 NIYDGCCQLDIQFSNLEELQVNYNN--DRSRDYTNPNLPAEQKGRS---SHPCYGDT-------- 213

  Fly   207 SHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQQQLVAPAQSHNLYQFKEPPLLGPGAAFPPFGA 271
                                                                    |.|:|...
plant   214 --------------------------------------------------------GVAYPQMA- 221

  Fly   272 PEYHTTTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLF 336
               :|:..     ||....||   |.|:.            |......::|..|:.|:.:.||||
plant   222 ---NTSAI-----AAAFGGGL---PPGIT------------GTNDRCTVLVSNLNADSIDEDKLF 263

  Fly   337 NLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVIN 401
            ||..||||:.|||.|:.|...|:|||||....|..|..|....: .|.::::.|||        :
plant   264 NLFSLYGNIVRIKLLRNKPDHALVQMGDGFQAELAVHFLKGAML-FGKRLEVNFSK--------H 319

  Fly   402 PFLLPDHSPSFKEYTGSKNNRFLSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPA 466
            |.:.|  .....:|..|..|||...|..:......|:|::|....|..:||::::.  ::::..|
plant   320 PNITP--GTDSHDYVNSNLNRFNRNAAKNYRYCCSPTKMIHLSTLPQDVTEEEVMN--HVQEHGA 380

  Fly   467 -TSVRLFPLKTERSSSGLIEFSNISQAVLAIMKCNHLPIEGKGTKFPFIMKLCFSSSKSM 525
             .:.::|.:..::.:  |::|.|..:|..|:: |.|....|..     |:::.||..:::
plant   381 VVNTKVFEMNGKKQA--LVQFENEEEAAEALV-CKHATSLGGS-----IIRISFSQLQTI 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	39/86 (45%)
		RRM3_hnRNPL_like	319..390	CDD:240870	28/70 (40%)
		RRM4_hnRNPL_like	437..519	CDD:240873	17/82 (21%)
PTB3	NP_001077672.1	hnRNP-L_PTB	5..427	CDD:273733	120/443 (27%)
		RRM1_PTBPH3	6..80	CDD:241131
		RRM2_PTBPH3	97..184	CDD:241136	40/86 (47%)
		RRM3_PTBPH3	244..319	CDD:241142	31/83 (37%)
		RRM4_PTBPH3	348..426	CDD:240872	17/87 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.880