DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sm and PTB2

DIOPT Version :9

Sequence 1:	NP_001246428.1	Gene:	sm / 37254	FlyBaseID:	FBgn0003435	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_200130.1	Gene:	PTB2 / 835399	AraportID:	AT5G53180	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	219	Identity:	73/219 - (33%)
Similarity:	107/219 - (48%)	Gaps:	42/219 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 DLRRKRPETTRPNHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIFKKN-GVQAMVEFDNLDA 131
            |.::..||    :::||.:|.|..|.:|:||||.:....|:|.:|.:|.|| ||||::::.::..
plant   235 DGKKMEPE----SNVLLASIENMQYAVTLDVLHMVFAAFGEVQKIAMFDKNGGVQALIQYSDVQT 295

  Fly   132 ATRARENLNGADIY-AGCCTLKIDYAKPEKLNVYKNEPDTSWDYTLSTVKEIGNGRSPLLQEPLY 195
            |..|:|.|.|..|| .|.|.|.|.|::...|::..|. |.|.|||:.      |...|:.|:|:.
plant   296 AVVAKEALEGHCIYDGGFCKLHITYSRHTDLSIKVNN-DRSRDYTMP------NPPVPMPQQPVQ 353

  Fly   196 VATLSTPQQ-HVSHQHHHHLRQQQQQQHQQQAPQQQPHPQ---------HLHHQQQLVAPAQSHN 250
            ......||| |.:...||      |||.|.|....||..|         |.|:    :||..|.:
plant   354 NPYAGNPQQYHAAGGSHH------QQQQQPQGGWVQPGGQGSMGMGGGGHNHY----MAPPSSSS 408

  Fly   251 LYQFKEPPLLGPGAAFPP--FGAP 272
            ::|       |||...||  :|.|
plant   409 MHQ-------GPGGHMPPQHYGGP 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	33/86 (38%)
		RRM3_hnRNPL_like	319..390	CDD:240870
		RRM4_hnRNPL_like	437..519	CDD:240873
PTB2	NP_200130.1	RRM1_PTBPH1_PTBPH2	16..96	CDD:241130
		RRM2_PTBPH1_PTBPH2	110..204	CDD:241135
		RRM3_PTBPH1_PTBPH2	243..339	CDD:241134	37/96 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920