Protein Alignment sm and ptbp3

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_009303446.1
• Gene: ptbp3 / 798982
• ZFINID: ZDB-GENE-091116-1
• Length: 522
• Species: Danio rerio
• Alignment Length: 557
• Identity: 136/557 - (24%)
• Similarity: 223/557 - (40%)
• Gaps: 140/557 - (25%)

  Fly    17 GGGATIVVTEGPQNKKIRTGVQQPGENDVHMHARSTPQQNQQQALMNKSNDDLRRKRPETTRPNH 81
            |....:::.:|.....|....::.....|:.:..:||....|...:..||   .|:......||.
Zfish    53 GKVTNLLMLKGKNQAFIEMASEEAAMTMVNYYTTATPHVRNQPVYIQYSN---HRELKTDNLPNQ 114

  Fly    82 -------------------------------------ILLFTIINPFYPITVDVLHKICHPHGQV 109
                                                 :|...:.|.:||::::|||:|....|.|
Zfish   115 GRAQAALQAVNAVHTGNMSLSGTATASDGGMMPGQSPVLRIIVENLYYPVSLEVLHQIFSKFGTV 179

  Fly   110 LRIVIFKKNG-VQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNV-YKNEPDTSW 172
            |:|:.|.||. .||::::.:...|..|:..|:|.:||.|||||:::::|...||| |.|  |.|.
Zfish   180 LKIITFTKNNQFQALLQYADPMNAHHAKVALDGQNIYNGCCTLRVEFSKLTSLNVKYNN--DKSR 242

  Fly   173 DYTLSTVKEIGNGRSPLLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLH 237
            |:|...:.. |:|      :|....|:.|
Zfish   243 DFTRLDLPS-GDG------QPTLDPTMQT------------------------------------ 264

  Fly   238 HQQQLVAPAQSHNLYQFKEPPLLG---PGAA--FPPFGAPEYHTTTPENWKGAAIHPTGLMKEPA 297
                           .|..|.::.   ||||  .|..|.|:...:. :...||    .|.:..|:
Zfish   265 ---------------AFGAPGIISSPYPGAAGFAPAIGFPQAGLSM-QAMPGA----LGPLTIPS 309

  Fly   298 GVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQM 362
            ..:.||.|....||  .|..:|::|..|:.|:.:..:||.|..:||:|.|:|.|..|:..|::||
Zfish   310 SAMTGRMAIHGMTP--TAIHSVLLVSNLNPDSISPHELFILFGVYGDVHRVKILFNKKENALIQM 372

  Fly   363 GDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLP----DHSPSFKEYTGSKNNRF 423
            .||...:..:.|||...: .|..|::..||...:.       ||    :.....|:::||..:||
Zfish   373 ADATQAQLAMSHLNGQRL-YGKVIRVTISKHQTVQ-------LPREGQEDQGLTKDFSGSPLHRF 429

  Fly   424 LSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPATS---VRLFPLKTERSSSGLIE 485
            ..|...:...|.|||..||..|.||..|:|.|      ||:.|:|   |:.|....:.....||:
Zfish   430 KKPGSKNFQNIFPPSATLHLSNIPPSTTDDFL------KDLFASSGYTVKAFKFFQKDRKMALIQ 488

  Fly   486 FSNISQAVLAIMKCNHLPIEGKGTKFPFIMKLCFSSS 522
            ..::.:|:.|::   ||.....|....  :::.||.|
Zfish   489 LGSVEEAIQALI---HLHNHDLGENHH--LRVSFSKS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	33/123 (27%)
		RRM3_hnRNPL_like	319..390	CDD:240870	24/70 (34%)
		RRM4_hnRNPL_like	437..519	CDD:240873	23/84 (27%)
ptbp3	XP_009303446.1	hnRNP-L_PTB	27..522	CDD:273733	136/557 (24%)
		RRM1_PTBP1_like	29..109	CDD:241132	10/58 (17%)
		RRM2_ROD1	148..250	CDD:241228	38/103 (37%)
		RRM_SF	329..421	CDD:302621	29/99 (29%)
		RRM_SF	442..522	CDD:302621	27/90 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920